Vaping and e-cigarette use. Mysterious lung manifestations and an epidemic

Electronic (e)-cigarette use and the practice of vaping has rapidly expanded both in adult smokers and previously nicotine naïve youths. Research has focused on harm reduction in adults using e-cigarettes to stop or reduce traditional cigarette use, but the short and long-term safety of these produc...

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Bibliographic Details
Published in:Current opinion in immunology 2020-10, Vol.66, p.143-150
Main Authors: Casey, Alicia M, Muise, Eleanor D, Crotty Alexander, Laura E
Format: Article
Language:English
Subjects:
Electronic Nicotine Delivery Systems
Humans
Lung Injury - chemically induced
Lung Injury - epidemiology
Vaping
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Summary:Electronic (e)-cigarette use and the practice of vaping has rapidly expanded both in adult smokers and previously nicotine naïve youths. Research has focused on harm reduction in adults using e-cigarettes to stop or reduce traditional cigarette use, but the short and long-term safety of these products has not been established. Vaping has more recently been associated with a growing list of pulmonary complications with the most urgent being the e-cigarette or vaping product use-associated lung injury (EVALI) epidemic. This review details the inhalant toxicology of vaping products, the described lung diseases associated with vaping with a focus on EVALI, and the predicted long-term consequences of e-cigarette use, including increased asthma severity.
ISSN:0952-7915
1879-0372
DOI:10.1016/j.coi.2020.10.003