The Potential of Polyethylene Terephthalate Glycol as Biomaterial for Bone Tissue Engineering

The search for materials with improved mechanical and biological properties is a major challenge in tissue engineering. This paper investigates, for the first time, the use of Polyethylene Terephthalate Glycol (PETG), a glycol-modified class of Polyethylene Terephthalate (PET), as a potential materi...

Full description

Saved in:
Bibliographic Details
Published in:Polymers 2020-12, Vol.12 (12), p.3045
Main Authors: Hassan, Mohamed H, Omar, Abdalla M, Daskalakis, Evangelos, Hou, Yanhao, Huang, Boyang, Strashnov, Ilya, Grieve, Bruce D, Bártolo, Paulo
Format: Article
Language:English
Subjects:
Additive manufacturing
Biological activity
Biological properties
Biomechanics
Biomedical materials
Bones
Carbon
Cell culture
Composite materials
Extrusion
Lasers
Mechanical properties
Nanoparticles
Penicillin
Phenols
Polycaprolactone
Polyethylene terephthalate
Polymers
Pore size
Porosity
Scaffolds
Software
Stem cells
Tissue engineering
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The search for materials with improved mechanical and biological properties is a major challenge in tissue engineering. This paper investigates, for the first time, the use of Polyethylene Terephthalate Glycol (PETG), a glycol-modified class of Polyethylene Terephthalate (PET), as a potential material for the fabrication of bone scaffolds. PETG scaffolds with a 0/90 lay-dawn pattern and different pore sizes (300, 350 and 450 µm) were produced using a filament-based extrusion additive manufacturing system and mechanically and biologically characterized. The performance of PETG scaffolds with 300 µm of pore size was compared with polycaprolactone (PCL). Results show that PETG scaffolds present significantly higher mechanical properties than PCL scaffolds, providing a biomechanical environment that promotes high cell attachment and proliferation.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym12123045