UV-initiated crosslinking of electrospun chitosan/poly(ethylene oxide) nanofibers doped with ZnO-nanoparticles: development of antibacterial nanofibrous hydrogel

UV-initiated crosslinking of electrospun poly(ethylene) oxide (PEO)/chitosan (CS) nanofibers doped with zinc oxide nanoparticles (ZnO-NPs) was performed using pentaerythritol triaclyrate (PETA) as the photoinitiator and crosslinker agent. The influence of the addition of PETA to the PEO/CS diameter...

Full description

Saved in:
Bibliographic Details
Published in:MRS communications 2020-12, Vol.10 (4), p.642-651
Main Authors: Estrada-Villegas, G.M., Del Río-De Vicente, J.I., Argueta-Figueroa, L., González-Pérez, G.
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Bacteria
Bacterial infections
Biocompatibility
Biomaterials
Biomedical materials
Cellulose
Characterization and Evaluation of Materials
Chitosan
Crosslinking
Electrospinning
Ethylene oxide
Hydrogels
Infections
Materials Engineering
Materials Science
Mechanical properties
Molecular weight
Morphology
Nanofibers
Nanoparticles
Nanotechnology
Photoinitiators
Polyethylene oxide
Polymer Sciences
Polymers
Polyvinyl alcohol
Reagents
Research Letters
Skin
Solvents
Tissue engineering
Wound healing
Zinc oxide
Zinc oxides
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:UV-initiated crosslinking of electrospun poly(ethylene) oxide (PEO)/chitosan (CS) nanofibers doped with zinc oxide nanoparticles (ZnO-NPs) was performed using pentaerythritol triaclyrate (PETA) as the photoinitiator and crosslinker agent. The influence of the addition of PETA to the PEO/CS diameter and crosslinking of nanofibers was evaluated. The effect of irradiation time on the morphology and swelling properties of the crosslinked nanofibers were investigated. For ZnO-NPs, the minimum inhibitory concentrations were found at 1 mg/mL, and the minimum bactericidal concentrations at 2 mg/mL for all the strains tested. The nanofibrous hydrogel antibacterial effect was tested. This material enters the realm of fibrous hydrogels which have potential use in several applications as in the biomedical area.
ISSN:2159-6859
2159-6867
DOI:10.1557/mrc.2020.74