FlyRNAi.org—the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

Abstract The FlyRNAi database at the Drosophila RNAi Screening Center and Transgenic RNAi Project (DRSC/TRiP) provides a suite of online resources that facilitate functional genomics studies with a special emphasis on Drosophila melanogaster. Currently, the database provides: gene-centric resources...

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Bibliographic Details
Published in:Nucleic acids research 2021-01, Vol.49 (D1), p.D908-D915
Main Authors: Hu, Yanhui, Comjean, Aram, Rodiger, Jonathan, Liu, Yifang, Gao, Yue, Chung, Verena, Zirin, Jonathan, Perrimon, Norbert, Mohr, Stephanie E
Format: Article
Language:English
Subjects:
Animals
Animals, Genetically Modified
Computational Biology - methods
Database Issue
Databases, Genetic
Drosophila melanogaster - genetics
Drosophila Proteins - genetics
Gene Expression Profiling - methods
Genome, Insect - genetics
Genomics - methods
Information Storage and Retrieval
Internet
RNA Interference
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Summary:Abstract The FlyRNAi database at the Drosophila RNAi Screening Center and Transgenic RNAi Project (DRSC/TRiP) provides a suite of online resources that facilitate functional genomics studies with a special emphasis on Drosophila melanogaster. Currently, the database provides: gene-centric resources that facilitate ortholog mapping and mining of information about orthologs in common genetic model species; reagent-centric resources that help researchers identify RNAi and CRISPR sgRNA reagents or designs; and data-centric resources that facilitate visualization and mining of transcriptomics data, protein modification data, protein interactions, and more. Here, we discuss updated and new features that help biological and biomedical researchers efficiently identify, visualize, analyze, and integrate information and data for Drosophila and other species. Together, these resources facilitate multiple steps in functional genomics workflows, from building gene and reagent lists to management, analysis, and integration of data.
ISSN:0305-1048
1362-4962
1362-4962
DOI:10.1093/nar/gkaa936