Prevalence of Inferior Vena Cava Compression in ADPKD

Kidney and liver cysts in autosomal dominant polycystic kidney disease (ADPKD) can compress the inferior vena cava (IVC), but IVC compression prevalence and its risk factors are unknown. Patients who have ADPKD (n = 216) with abdominal magnetic resonance imaging (MRI) studies and age-/sex-matched co...

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Bibliographic Details
Published in:Kidney international reports 2021-01, Vol.6 (1), p.168-178
Main Authors: Yin, Xiaorui, Blumenfeld, Jon D., Riyahi, Sadjad, Luo, Xianfu, Rennert, Hanna, Barash, Irina, Prince, Martin R.
Format: Article
Language:English
Subjects:
ADPKD
azygos vein
Clinical Research
DVT
hypotension
IVC compression
Mayo Clinic Classification
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Summary:Kidney and liver cysts in autosomal dominant polycystic kidney disease (ADPKD) can compress the inferior vena cava (IVC), but IVC compression prevalence and its risk factors are unknown. Patients who have ADPKD (n = 216) with abdominal magnetic resonance imaging (MRI) studies and age-/sex-matched controls (n = 216) were evaluated for IVC compression as well as azygous vein diameter (a marker of collateral blood flow) and IVC aspect ratio (left-to-right dimension divided by anterior-to-posterior dimension with a value of 1 corresponding to a circular (high pressure) IVC caudal to compression. Severe IVC compression (≥70%) was observed in 33 (15%) ADPKD subjects and mild compression (≥50% to 40 years old, with Mayo Clinic class 1D/E, and in females with ht-LV > 2000 ml/m. [Display omitted]
ISSN:2468-0249
2468-0249
DOI:10.1016/j.ekir.2020.10.027