Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

• Published in: ACS pharmacology & translational science 2021-02, Vol.4 (1), p.8-54
• Main Authors: Balasubramaniam, Bhuvaneshwari, Prateek, Ranjan, Sudhir, Saraf, Mohit, Kar, Prasenjit, Singh, Surya Pratap, Thakur, Vijay Kumar, Singh, Anand, Gupta, Raju Kumar
• Format: Article
• Language: English
• Subjects: Review
• ISSN: 2575-9108; 2575-9108
• DOI: 10.1021/acsptsci.0c00174

The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO2, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.