Genetic Diversity of SARS-CoV2 and Environmental Settings: Possible Association with Neurological Disorders

The new coronavirus (CoV), called novel coronavirus disease 2019 (COVID-19), belongs to the Coronaviridae family which was originated from the sea market in Wuhan city in China, at the end of the year 2019. COVID-19 and severe acute respiratory syndrome (SARS) are belonging to the same family (Coron...

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Bibliographic Details
Published in:Molecular neurobiology 2021-05, Vol.58 (5), p.1917-1931
Main Authors: Hasana, Sharifa, Hossain, Md. Farhad, Jalouli, Maroua, Kabir, Md. Tanvir, Uddin, Md. Giash, Wahed, Mir Imam Ibne, Behl, Tapan, Bin-Jumah, May N., Abdel-Daim, Mohamed M., Aleya, Lotfi, Uddin, Md. Sahab
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Cell Biology
Climate effects
Comorbidity
Coronaviridae
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - genetics
Disease transmission
Environmental Sciences
Genetic diversity
Genetic Variation
Humans
Morbidity
Nervous System Diseases - epidemiology
Nervous System Diseases - genetics
Neurobiology
Neurological diseases
Neurological disorders
Neurology
Neurosciences
Pandemics
SARS-CoV-2 - genetics
Severe acute respiratory syndrome coronavirus 2
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Summary:The new coronavirus (CoV), called novel coronavirus disease 2019 (COVID-19), belongs to the Coronaviridae family which was originated from the sea market in Wuhan city in China, at the end of the year 2019. COVID-19 and severe acute respiratory syndrome (SARS) are belonging to the same family (Coronaviridae). The current outbreak of COVID-19 creates public concern and threats all over the world and now it spreads out to more than 250 countries and territories. The researchers and scientists from all over the world are trying to find out the therapeutic strategies to abate the morbidity and mortality rate of the COVID-19 pandemic. The replication, spreading, and severity of SARS-CoV2 depend on environmental settings. Noteworthy, meteorological parameters are considered as crucial factors that affect respiratory infectious disorders, although the controversial effect of the meteorological parameter is exposed against COVID-19. Besides, COVID-19 accelerates the pathogenesis of the neurological disorders. However, the pathogenic mechanisms between COVID-19 and neurological disorders are still unclear. Hence, this review is focused on the genomics and ecology of SARS-CoV2 and elucidated the effects of climatic factors on the progression of COVID-19. This review also critically finds out the vulnerability between COVID-19 and neurological disorders based on the latest research data.
ISSN:0893-7648
1559-1182
DOI:10.1007/s12035-020-02239-z