Impact of nutritional index on long-term outcomes of elderly patients with coronary artery disease: sub-analysis of the SHINANO 5 year registry

Nutritional status is a novel approach to prognostic assessment in patients with cardiovascular disease. However, assessment of nutritional status in elderly patients is challenging due to the significant differences between young patients. The TCBI (Triglycerides × Total cholesterol × Body Weight I...

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Published in:Heart and vessels 2021-01, Vol.36 (1), p.7-13
Main Authors: Maruyama, Shusaku, Ebisawa, Souichiro, Miura, Takashi, Yui, Hisanori, Kashiwagi, Daisuke, Nagae, Ayumu, Sakai, Takahiro, Kato, Tamon, Saigusa, Tatsuya, Okada, Ayako, Motoki, Hirohiko, Kuwahara, Koichiro
Format: Article
Language:English
Subjects:
Biomedical Engineering and Bioengineering
Body weight
Cardiac Surgery
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cerebral infarction
Cholesterol
Confidence intervals
Coronary artery
Coronary artery disease
Coronary vessels
Heart diseases
Medicine
Medicine & Public Health
Multivariate analysis
Myocardial infarction
Nutrition assessment
Nutritional status
Older people
Original
Original Article
Triglycerides
Vascular Surgery
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creator Maruyama, Shusaku
Ebisawa, Souichiro
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Yui, Hisanori
Kashiwagi, Daisuke
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Kato, Tamon
Saigusa, Tatsuya
Okada, Ayako
Motoki, Hirohiko
Kuwahara, Koichiro
description Nutritional status is a novel approach to prognostic assessment in patients with cardiovascular disease. However, assessment of nutritional status in elderly patients is challenging due to the significant differences between young patients. The TCBI (Triglycerides × Total cholesterol × Body Weight Index) is a novel and simple nutritional index for predicting long-term outcomes in patients with coronary artery disease. This retrospective study evaluated the efficacy of TCBI in 597 elderly (≥ 75 years) patients enrolled in the SHINANO 5 year registry. The SHINANO 5 year registry, a prospective observational multicenter cohort study, had enrolled 1501 consecutive patients who underwent elective/urgent percutaneous coronary intervention (PCI). In this study, patients were categorized into TCBI quartile groups. The primary endpoints were the occurrence of major adverse cardiac and cerebrovascular events (MACCE), including all-cause death, stroke, and myocardial infarction at 5 year. The mean duration of follow up was 4.3 ± 1.7 years. The average patient age was 80.9 ± 4.3 years. MACCE was observed in 61 (40.9%) patients in the lowest TCBI quartile group. Kaplan–Meier analysis demonstrated an inverse relationship between MACCE and TCBI (log-lank P  
doi_str_mv 10.1007/s00380-020-01659-0
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MACCE was observed in 61 (40.9%) patients in the lowest TCBI quartile group. Kaplan–Meier analysis demonstrated an inverse relationship between MACCE and TCBI (log-lank P  &lt; 0.001). Multivariate analysis demonstrated that low TCBI significantly predicted the incidence of MACCE (hazard ratio: 1.44, 95% confidence interval: 1.03–2.00; P  = 0.031). 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subjects Biomedical Engineering and Bioengineering
Body weight
Cardiac Surgery
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cerebral infarction
Cholesterol
Confidence intervals
Coronary artery
Coronary artery disease
Coronary vessels
Heart diseases
Medicine
Medicine & Public Health
Multivariate analysis
Myocardial infarction
Nutrition assessment
Nutritional status
Older people
Original
Original Article
Triglycerides
Vascular Surgery
title Impact of nutritional index on long-term outcomes of elderly patients with coronary artery disease: sub-analysis of the SHINANO 5 year registry
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