Factors Associated with Mortality among Hospitalized Patients with COVID-19: A Retrospective Cohort Study

Information on the risk factors for COVID-19 mortality in low- and middle-income countries is still scarce. In this retrospective cohort study, we analyzed the factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil. Logistic regression was used to identify facto...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2021-01, Vol.104 (1), p.103-105
Main Authors: Martins-Filho, Paulo Ricardo, Antunes de Souza Araújo, Adriano, Pereira, Luciana Xavier, Quintans-Júnior, Lucindo José, de Souza Barboza, Waneska, Cavalcante, Taise Ferreira, Feitosa de Souza, Mércia, de Oliveira Góes, Marco Aurélio, Santos, Victor Santana
Format: Article
Language:English
Subjects:
Brazil - epidemiology
Cohort analysis
Cohort Studies
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - mortality
Humans
Inpatients
Mortality
Poverty
Retrospective Studies
Risk Factors
SARS-CoV-2
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Summary:Information on the risk factors for COVID-19 mortality in low- and middle-income countries is still scarce. In this retrospective cohort study, we analyzed the factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil. Logistic regression was used to identify factors independently associated with mortality, including gender, age, and the presence of underlying medical conditions. A total of 1,207 patients were included in the analysis, and a 1.5-fold increase in COVID-19 mortality was found among patients aged > 65 years with hypertension and diabetes (odds ratio [OR]: 1.50, 95% CI: 1.02-2.19). Moreover, infectious disease (OR: 4.31, 95% CI: 1.39-13.39), kidney disease (OR: 2.59, 95% CI: 1.27-5.27), and heart disease (OR: 2.00, 95% CI: 1.31-3.04) were also predictive for COVID-19 in-hospital death. This large cohort provides important data on potential factors associated with COVID-19 mortality in Brazil.
ISSN:0002-9637
1476-1645
DOI:10.4269/AJTMH.20-1170