Prevalence and Antimicrobial Susceptibility Profiles of Microorganisms Associated with Lower Reproductive Tract Infections in Women from Southern Poland-Retrospective Laboratory-Based Study

• Published in: International journal of environmental research and public health 2021-01, Vol.18 (1), p.335
• Main Authors: Wójkowska-Mach, Jadwiga, Pomorska-Wesołowska, Monika, Romanik, Małgorzata, Romaniszyn, Dorota
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age; Aged; Antibiotics; Antiinfectives and antibacterials; Antimicrobial agents; Bacilli; Bacteria; Candidiasis; Candidiasis, Vulvovaginal - epidemiology; Criteria; Disease transmission; Drug resistance; Drug Resistance, Bacterial; Dysbacteriosis; E coli; Epidemiology; Etiology; Female; Genital tract; Gram-positive cocci; Humans; Infections; Inflammation; Medical laboratories; Microbiota; Microorganisms; Middle Aged; Penicillin; Physicians; Poland - epidemiology; Prevalence; Pruritus; Reproductive system; Reproductive Tract Infections - microbiology; Retrospective Studies; Sexually transmitted diseases; STD; Streptococcus agalactiae; Streptococcus infections; Streptogramin B; Vagina; Vaginitis; Vaginosis; Vaginosis, Bacterial - epidemiology; Vulvovaginitis; Womens health; Yeast; Yeasts; Young Adult
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph18010335

Female infections affecting the genital tract include sexually transmitted diseases, endogenous infections such as vulvovaginal candidiasis, bacterial vaginosis (BV) or aerobic vaginitis (AV) and healthcare-associated infections. The aim of the study was to analyze the etiological factors of the vaginal dysbacteriosis, and the antimicrobial susceptibility of the dominant bacterial and fungal infections in different age groups of outpatient women from the Silesian Region. A retrospective laboratory-based multi-center study encompassed 4994 women of different ages in Silesian Voivodeship, in the south of Poland; patients who had vaginal swabs collected as per physicians' orders during the period from 1 January 2017 until 30 June 2018 were included in the study. The inclusion criteria were: non-hospitalized female, aged ≤80, with suspected vulvovaginal candidiasis or bacterial vaginosis and clinical sings of infections. Gram-positive cocci were the ones most often isolated: (29.2%) and (13.1%), followed by bacilli from the Enterobacteriaceae group, including (26.3%). The presence of was confirmed in 13.1%, slightly more often in the 45-80 age group, and in 6.4%, most often in women aged 15-24. The prevalence of yeast-like infections was 24.3%, accounted for 78.3%, whereas among spp.- dominated (14.9%) followed by (3.8%). The highest resistance was observed only in Streptococcus agalactiae as the MLSB mechanism (Macrolide-lincosamide-streptogramin B) was identified in 38.6% of strains. The prevalence of vulvovaginal candidiasis was 24.3%, the highest in women aged 15-44. Drug resistance in studied vulvovaginitis was associated only with . A high proportion of yeast-like aetiology was found, probably associated with recurrent infections. In the analyzed cases only the Amsel criteria and culture methods were used for diagnosis without preparations and microbiological Nugent criteria.