The influence of animal species, gender and tissue on the structural, biophysical, biochemical and biological properties of collagen sponges

Although collagen type I is extensively used in biomedicine, no study to-date has assessed how the properties of the produced scaffolds are affected as a function of species, gender and tissue from which the collagen was extracted. Herein, we extracted and characterised collagen from porcine and bov...

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Published in:Journal of materials science. Materials in medicine 2021, Vol.32 (1), p.12-12, Article 12
Main Authors: Sorushanova, Anna, Skoufos, Ioannis, Tzora, Athina, Mullen, Anne Maria, Zeugolis, Dimitrios I.
Format: Article
Language:English
Subjects:
Animal species
Animal tissues
Biocompatibility Studies
Biological properties
Biomaterials
Biomedical Engineering and Bioengineering
Biomedical materials
Ceramics
Chemistry and Materials Science
Collagen
Collagen (type I)
Composites
Compression
Denaturation
Fibroblasts
Gender
Glass
Materials Science
Monocytes
Natural Materials
Polymer Sciences
Regenerative Medicine/Tissue Engineering
Sponges
Surfaces and Interfaces
Swelling ratio
Thin Films
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Skoufos, Ioannis
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Zeugolis, Dimitrios I.
description Although collagen type I is extensively used in biomedicine, no study to-date has assessed how the properties of the produced scaffolds are affected as a function of species, gender and tissue from which the collagen was extracted. Herein, we extracted and characterised collagen from porcine and bovine, male and female and skin and tendon tissues and we subsequently fabricated and assessed the structural, biophysical, biochemical and biological properties of collagen sponges. All collagen preparations were of similar purity and free-amine content ( p  > 0.05). In general, the porcine groups yielded more collagen; had higher ( p  
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source Springer Nature - SpringerLink Journals - Fully Open Access
subjects Animal species
Animal tissues
Biocompatibility Studies
Biological properties
Biomaterials
Biomedical Engineering and Bioengineering
Biomedical materials
Ceramics
Chemistry and Materials Science
Collagen
Collagen (type I)
Composites
Compression
Denaturation
Fibroblasts
Gender
Glass
Materials Science
Monocytes
Natural Materials
Polymer Sciences
Regenerative Medicine/Tissue Engineering
Sponges
Surfaces and Interfaces
Swelling ratio
Thin Films
title The influence of animal species, gender and tissue on the structural, biophysical, biochemical and biological properties of collagen sponges
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