Prognostic significance of nutritional markers in metastatic gastric and esophageal adenocarcinoma

Background Malnutrition and sarcopenia are poor prognostic factors in many cancers. Studies in gastric and esophageal (GE) cancer have focused on curative intent patients. This study aims to evaluate the prognostic utility of malnutrition and sarcopenia in de novo metastatic GE adenocarcinoma. Metho...

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Bibliographic Details
Published in:Cancer medicine (Malden, MA) MA), 2021-01, Vol.10 (1), p.199-207
Main Authors: Ma, Lucy X., Taylor, Kirsty, Espin‐Garcia, Osvaldo, Anconina, Reut, Suzuki, Chihiro, Allen, Michael J., Honorio, Marta, Bach, Yvonne, Allison, Frances, Chen, Eric X., Brar, Savtaj, Swallow, Carol J., Yeung, Jonathan, Darling, Gail E., Wong, Rebecca, Kalimuthu, Sangeetha N., Jang, Raymond W., Veit‐Haibach, Patrick, Elimova, Elena
Format: Article
Language:English
Subjects:
Adenocarcinoma
Body mass index
Cancer
Chemotherapy
Clinical Cancer Research
Computed tomography
Esophageal cancer
Esophagus
Gastric cancer
Lymphatic system
Malnutrition
Medical imaging
Medical prognosis
Metastases
Metastasis
Musculoskeletal system
Nutrition
Nutritional status
Original Research
Overweight
Patients
prognosis
Radiation therapy
Sarcopenia
Skeletal muscle
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Summary:Background Malnutrition and sarcopenia are poor prognostic factors in many cancers. Studies in gastric and esophageal (GE) cancer have focused on curative intent patients. This study aims to evaluate the prognostic utility of malnutrition and sarcopenia in de novo metastatic GE adenocarcinoma. Methods Patients with de novo metastatic GE adenocarcinoma seen at the Princess Margaret Cancer Centre from 2010 to 2016 with an available pre‐treatment abdominal computed tomography (CT) were included. Malnutrition was defined as nutritional risk index (NRI)
ISSN:2045-7634
2045-7634
DOI:10.1002/cam4.3604