Rotational thromboelastometry in young, previously healthy patients with SARS-Cov2

In a series of 313 patients who had ROTEM prior to major non-cardiac surgery, for example, 10 patients with postoperative thromboembolic complications had significantly higher preoperative levels of maximum clot firmness (MCF) and significantly lower clot formation time (CFT) [4]. Initial laboratory...

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Bibliographic Details
Published in:Journal of clinical anesthesia 2020-12, Vol.67, p.110038-110038, Article 110038
Main Authors: Lazar, Michael, Tomey, Matthew I., Ghia, Samit, Katz, Daniel, Derr, Kelly, Narula, Jagat, Bhatt, Himani V.
Format: Article
Language:English
Subjects:
Adult
Anticoagulants - therapeutic use
Authorship
Blood Coagulation Disorders - etiology
Blood Coagulation Disorders - prevention & control
Correspondence
COVID hypercoagulability
COVID-19
COVID-19 - blood
Enoxaparin - therapeutic use
Heparin - therapeutic use
Humans
Laboratories
Patients
Pyrazoles - therapeutic use
Pyridones - therapeutic use
ROTEM
Thrombelastography - methods
Thromboelastometry
Thromboembolism
Thrombosis - etiology
Thrombosis - prevention & control
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Summary:In a series of 313 patients who had ROTEM prior to major non-cardiac surgery, for example, 10 patients with postoperative thromboembolic complications had significantly higher preoperative levels of maximum clot firmness (MCF) and significantly lower clot formation time (CFT) [4]. Initial laboratory studies were notable for normal levels of platelets, PT and PTT in both cases; elevated levels of fibrinogen (653 mg/dL and 820 mg/dL; normal, 212–516 mg/dL); and elevated levels of D-DIMER (0.76 μg/mL and 1.33 μg/mL; normal,
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2020.110038