Analysis of Ranitidine-Associated N-Nitrosodimethylamine Production Under Simulated Physiologic Conditions

This study characterizes conditions of N- nitrosodimethylamine production under simulated physiologic gastric states.

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Bibliographic Details
Published in:JAMA network open 2021-01, Vol.4 (1), p.e2034766
Main Authors: Braunstein, Lior Z, Kantor, Elizabeth D, O'Connell, Kelli, Hudspeth, Amber Jessop, Wu, Qian, Zenzola, Nicola, Light, David Y
Format: Article
Language:English
Subjects:
Carcinogens - chemistry
Chromatography, Liquid
Dimethylnitrosamine - chemistry
Hydrogen-Ion Concentration
Mass Spectrometry
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Pharmacy and Clinical Pharmacology
Ranitidine - chemistry
Research Letter
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Description
Summary:This study characterizes conditions of N- nitrosodimethylamine production under simulated physiologic gastric states.
ISSN:2574-3805
2574-3805
DOI:10.1001/jamanetworkopen.2020.34766