Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction

A 15-year-old boy diagnosed as case of cervical kyphosis, atlantoaxial dislocation, and hypofibrinogenemia was posted for corrective surgery under general anesthesia. His preoperative plasma fibrinogen levels and other coagulation profile were deranged. He was diagnosed with type 1 congenital fibrin...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pediatric neurosciences 2020-07, Vol.15 (3), p.322-324
Main Authors: Tyagi, Mayank, Kapoor, Indu, Rath, Girija P
Format: Article
Language:English
Subjects:
Biological products
Case Report
Fibrin
Fibrinogen
Genetic disorders
Health aspects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443
cites cdi_FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443
container_end_page 324
container_issue 3
container_start_page 322
container_title Journal of pediatric neurosciences
container_volume 15
creator Tyagi, Mayank
Kapoor, Indu
Rath, Girija P
description A 15-year-old boy diagnosed as case of cervical kyphosis, atlantoaxial dislocation, and hypofibrinogenemia was posted for corrective surgery under general anesthesia. His preoperative plasma fibrinogen levels and other coagulation profile were deranged. He was diagnosed with type 1 congenital fibrinogen abnormality, that is, hypofibrinogenemia. Preoperative blood products including cryoprecipitates were transfused to correct fibrinogen levels and coagulation profile. Cryoprecipitate was transfused at the dose of 1 bag per 10kg body weight per day. During intraoperative period, blood products were transfused following blood loss of 1100mL. Postoperatively the repeat laboratory investigations after 20 h revealed normal PF levels (211 mg/dL) with normal coagulation profile. He was discharged five days later with the uncomplicated postoperative course.
doi_str_mv 10.4103/jpn.JPN_59_20
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7847096</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A642099481</galeid><sourcerecordid>A642099481</sourcerecordid><originalsourceid>FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443</originalsourceid><addsrcrecordid>eNptkU1vGyEQhlHVqPloj71WSD2vAwu7C5dKlpMmqZyPQ3tGLDusiXbBgo0j__tixbUayeIADM-8w8yL0FdKZpwSdvm89rNfTw-qkqokH9AZlVIUTHLxMZ8FbQra8OoUnaf0TAiveck_oVPGKkZlJc9QP_eQphVMzuB77XUPI_gJB4u1x_MuDJDMLvDqphW-3a6DdW10PvTgYXQaP4U0QYdtiHgBceOMHvAV5Ovopi1ehBjBTC74z-jE6iHBl_1-gf78vP69uC2Wjzd3i_myMEzIqQBBmLBSEl5qUwvTEmPqtqw0dE1X66YmmnambFldiRJa3TZNzpOcVl1pJefsAv14012_tCN0u79HPah1dKOOWxW0U-9fvFupPmxUI3hDZJ0Fvr8J9HoA5bwNGTOjS0bN8_RILiZopooj1G4oWTN4sC6H3_GzI3xeXZ6iOZqwL2BiSCmCPbRAidoZr7Lx6mB85r_93_eB_uc0-wsfyKv3</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Tyagi, Mayank ; Kapoor, Indu ; Rath, Girija P</creator><creatorcontrib>Tyagi, Mayank ; Kapoor, Indu ; Rath, Girija P</creatorcontrib><description>A 15-year-old boy diagnosed as case of cervical kyphosis, atlantoaxial dislocation, and hypofibrinogenemia was posted for corrective surgery under general anesthesia. His preoperative plasma fibrinogen levels and other coagulation profile were deranged. He was diagnosed with type 1 congenital fibrinogen abnormality, that is, hypofibrinogenemia. Preoperative blood products including cryoprecipitates were transfused to correct fibrinogen levels and coagulation profile. Cryoprecipitate was transfused at the dose of 1 bag per 10kg body weight per day. During intraoperative period, blood products were transfused following blood loss of 1100mL. Postoperatively the repeat laboratory investigations after 20 h revealed normal PF levels (211 mg/dL) with normal coagulation profile. He was discharged five days later with the uncomplicated postoperative course.</description><identifier>ISSN: 1817-1745</identifier><identifier>EISSN: 1998-3948</identifier><identifier>DOI: 10.4103/jpn.JPN_59_20</identifier><identifier>PMID: 33531959</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Biological products ; Case Report ; Fibrin ; Fibrinogen ; Genetic disorders ; Health aspects</subject><ispartof>Journal of pediatric neurosciences, 2020-07, Vol.15 (3), p.322-324</ispartof><rights>Copyright: © 2020 Journal of Pediatric Neurosciences.</rights><rights>COPYRIGHT 2020 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright: © 2020 Journal of Pediatric Neurosciences 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443</citedby><cites>FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847096/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847096/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33531959$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tyagi, Mayank</creatorcontrib><creatorcontrib>Kapoor, Indu</creatorcontrib><creatorcontrib>Rath, Girija P</creatorcontrib><title>Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction</title><title>Journal of pediatric neurosciences</title><addtitle>J Pediatr Neurosci</addtitle><description>A 15-year-old boy diagnosed as case of cervical kyphosis, atlantoaxial dislocation, and hypofibrinogenemia was posted for corrective surgery under general anesthesia. His preoperative plasma fibrinogen levels and other coagulation profile were deranged. He was diagnosed with type 1 congenital fibrinogen abnormality, that is, hypofibrinogenemia. Preoperative blood products including cryoprecipitates were transfused to correct fibrinogen levels and coagulation profile. Cryoprecipitate was transfused at the dose of 1 bag per 10kg body weight per day. During intraoperative period, blood products were transfused following blood loss of 1100mL. Postoperatively the repeat laboratory investigations after 20 h revealed normal PF levels (211 mg/dL) with normal coagulation profile. He was discharged five days later with the uncomplicated postoperative course.</description><subject>Biological products</subject><subject>Case Report</subject><subject>Fibrin</subject><subject>Fibrinogen</subject><subject>Genetic disorders</subject><subject>Health aspects</subject><issn>1817-1745</issn><issn>1998-3948</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNptkU1vGyEQhlHVqPloj71WSD2vAwu7C5dKlpMmqZyPQ3tGLDusiXbBgo0j__tixbUayeIADM-8w8yL0FdKZpwSdvm89rNfTw-qkqokH9AZlVIUTHLxMZ8FbQra8OoUnaf0TAiveck_oVPGKkZlJc9QP_eQphVMzuB77XUPI_gJB4u1x_MuDJDMLvDqphW-3a6DdW10PvTgYXQaP4U0QYdtiHgBceOMHvAV5Ovopi1ehBjBTC74z-jE6iHBl_1-gf78vP69uC2Wjzd3i_myMEzIqQBBmLBSEl5qUwvTEmPqtqw0dE1X66YmmnambFldiRJa3TZNzpOcVl1pJefsAv14012_tCN0u79HPah1dKOOWxW0U-9fvFupPmxUI3hDZJ0Fvr8J9HoA5bwNGTOjS0bN8_RILiZopooj1G4oWTN4sC6H3_GzI3xeXZ6iOZqwL2BiSCmCPbRAidoZr7Lx6mB85r_93_eB_uc0-wsfyKv3</recordid><startdate>20200701</startdate><enddate>20200701</enddate><creator>Tyagi, Mayank</creator><creator>Kapoor, Indu</creator><creator>Rath, Girija P</creator><general>Medknow Publications and Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20200701</creationdate><title>Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction</title><author>Tyagi, Mayank ; Kapoor, Indu ; Rath, Girija P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Biological products</topic><topic>Case Report</topic><topic>Fibrin</topic><topic>Fibrinogen</topic><topic>Genetic disorders</topic><topic>Health aspects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tyagi, Mayank</creatorcontrib><creatorcontrib>Kapoor, Indu</creatorcontrib><creatorcontrib>Rath, Girija P</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of pediatric neurosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tyagi, Mayank</au><au>Kapoor, Indu</au><au>Rath, Girija P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction</atitle><jtitle>Journal of pediatric neurosciences</jtitle><addtitle>J Pediatr Neurosci</addtitle><date>2020-07-01</date><risdate>2020</risdate><volume>15</volume><issue>3</issue><spage>322</spage><epage>324</epage><pages>322-324</pages><issn>1817-1745</issn><eissn>1998-3948</eissn><abstract>A 15-year-old boy diagnosed as case of cervical kyphosis, atlantoaxial dislocation, and hypofibrinogenemia was posted for corrective surgery under general anesthesia. His preoperative plasma fibrinogen levels and other coagulation profile were deranged. He was diagnosed with type 1 congenital fibrinogen abnormality, that is, hypofibrinogenemia. Preoperative blood products including cryoprecipitates were transfused to correct fibrinogen levels and coagulation profile. Cryoprecipitate was transfused at the dose of 1 bag per 10kg body weight per day. During intraoperative period, blood products were transfused following blood loss of 1100mL. Postoperatively the repeat laboratory investigations after 20 h revealed normal PF levels (211 mg/dL) with normal coagulation profile. He was discharged five days later with the uncomplicated postoperative course.</abstract><cop>India</cop><pub>Medknow Publications and Media Pvt. Ltd</pub><pmid>33531959</pmid><doi>10.4103/jpn.JPN_59_20</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1817-1745
ispartof Journal of pediatric neurosciences, 2020-07, Vol.15 (3), p.322-324
issn 1817-1745
1998-3948
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7847096
source Publicly Available Content Database; PubMed Central
subjects Biological products
Case Report
Fibrin
Fibrinogen
Genetic disorders
Health aspects
title Anesthetic Management of an Adolescent with Hypofibrinogenemia Posted for Cervical Deformity Correction
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T19%3A13%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Anesthetic%20Management%20of%20an%20Adolescent%20with%20Hypofibrinogenemia%20Posted%20for%20Cervical%20Deformity%20Correction&rft.jtitle=Journal%20of%20pediatric%20neurosciences&rft.au=Tyagi,%20Mayank&rft.date=2020-07-01&rft.volume=15&rft.issue=3&rft.spage=322&rft.epage=324&rft.pages=322-324&rft.issn=1817-1745&rft.eissn=1998-3948&rft_id=info:doi/10.4103/jpn.JPN_59_20&rft_dat=%3Cgale_pubme%3EA642099481%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c389t-e8038f99042ac68cb0cc6b25aed7d6a760a1dc2b36582ebab773899415d2f9443%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/33531959&rft_galeid=A642099481&rfr_iscdi=true