Evaluation of Anesthetic and Analgesic Effects of Intrathecal Administration of Tramadol vs Fentanyl

The aim of this study was to examine the anesthetic and analgesic effects of intrathecal tramadol compared with intrathecal fentanyl added to bupivacaine and that of a placebo added to bupivacaine in patients undergoing elective transurethral procedures. The anesthetic and analgesic efficacy of intr...

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Bibliographic Details
Published in:Şişli Etfal Hastanesi tıp bülteni 2019-01, Vol.53 (1), p.16-20
Main Authors: Ozer, Surhan, Turk, Hacer Sebnem
Format: Article
Language:English
Subjects:
Analgesics
Fentanyl
Original Research
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Summary:The aim of this study was to examine the anesthetic and analgesic effects of intrathecal tramadol compared with intrathecal fentanyl added to bupivacaine and that of a placebo added to bupivacaine in patients undergoing elective transurethral procedures. The anesthetic and analgesic efficacy of intrathecal tramadol hydrochloride (HCL) was assessed against a local anesthetic in this prospective, double-blind, randomized study of 146 American Society of Anesthesiologists classification I-III patients who underwent an elective transurethral procedure. A lumbar intrathecal block was performed using bupivacaine heavy 0.5 % combined with either tramadol HCL, fentanyl, or saline for surgery. Each group received 12.5 mg bupivacaine with 50 μg (1 mL) fentanyl, 12.5 mg bupivacaine with 10 mg (1 mL) tramadol, or 12.5 mg bupivacaine with 1 mL preservative-free saline. The saline group experienced more pain than patients in the tramadol HCL and fentanyl groups (p
ISSN:1302-7123
1308-5123
DOI:10.14744/SEMB.2018.19327