Brinzolamide/brimonidine fixed-dose combination bid as an adjunct to a prostaglandin analog for open-angle glaucoma/ocular hypertension

Purpose: To evaluate the additive intraocular pressure–lowering effect of twice-daily brinzolamide 1%/brimonidine 0.2% fixed-dose combination (BBFC) as an adjunct to a prostaglandin analog (PGA) in patients with open-angle glaucoma or ocular hypertension insufficiently controlled with PGA monotherap...

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Bibliographic Details
Published in:European journal of ophthalmology 2021-01, Vol.31 (1), p.103-111
Main Authors: Topouzis, Fotis, Goldberg, Ivan, Bell, Katharina, Tatham, Andrew J, Ridolfi, Antonia, Hubatsch, Douglas, Nicolela, Marcelo, Denis, Phillipe, Lerner, S Fabian
Format: Article
Language:English
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Summary:Purpose: To evaluate the additive intraocular pressure–lowering effect of twice-daily brinzolamide 1%/brimonidine 0.2% fixed-dose combination (BBFC) as an adjunct to a prostaglandin analog (PGA) in patients with open-angle glaucoma or ocular hypertension insufficiently controlled with PGA monotherapy. Methods: In this Phase 4, double-masked trial, patients aged ⩾18 years, with a mean intraocular pressure of ⩾19 and
ISSN:1120-6721
1724-6016
DOI:10.1177/1120672119878044