Evidence of early circulation of SARS-CoV-2 in France: findings from the population-based “CONSTANCES” cohort

Using serum samples routinely collected in 9144 adults from a French general population-based cohort, we identified 353 participants with a positive anti-SARS-CoV-2 IgG test, among whom 13 were sampled between November 2019 and January 2020 and were confirmed by neutralizing antibodies testing. Inve...

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Bibliographic Details
Published in:European journal of epidemiology 2021-02, Vol.36 (2), p.219-222
Main Authors: Carrat, Fabrice, Figoni, Julie, Henny, Joseph, Desenclos, Jean-Claude, Kab, Sofiane, de Lamballerie, Xavier, Zins, Marie
Format: Article
Language:English
Subjects:
Adult
Aged
Antibodies
Cardiology
Cohort Studies
Correspondence
COVID-19
COVID-19 - blood
COVID-19 - epidemiology
Epidemiology
Female
France - epidemiology
Humans
Immunoglobulin G
Infectious Diseases
Life Sciences
Male
Medicine
Medicine & Public Health
Middle Aged
Oncology
Public Health
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Viral diseases
Young Adult
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Summary:Using serum samples routinely collected in 9144 adults from a French general population-based cohort, we identified 353 participants with a positive anti-SARS-CoV-2 IgG test, among whom 13 were sampled between November 2019 and January 2020 and were confirmed by neutralizing antibodies testing. Investigations in 11 of these participants revealed experience of symptoms possibly related to a SARS-CoV-2 infection or situations at risk of potential SARS-CoV-2 exposure. This suggests early circulation of SARS-CoV-2 in Europe.
ISSN:0393-2990
1573-7284
DOI:10.1007/s10654-020-00716-2