Comparison of the anesthetic effects between 5 mg/kg of alfaxalone and 10 mg/kg of propofol administered intravenously in cats

To compare the anesthetic effects after intravenous administration of alfaxalone or propofol without premedication, either alfaxalone (5 mg/kg) or propofol (10 mg/kg) was administered intravenously over 120 sec in 6 cats. Each cat received the alternate treatment at least a 7-day interval. Anestheti...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Veterinary Medical Science 2021, Vol.83(1), pp.73-77
Main Authors: TAMURA, Jun, OYAMA, Norihiko, FUKUI, Sho, YAMASHITA, Kazuto
Format: Article
Language:English
Subjects:
Adverse events
alfaxalone
anesthetic induction
Apnea
Ataxia
feline
Hypoxemia
Intravenous administration
Intubation
Physiology
Propofol
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To compare the anesthetic effects after intravenous administration of alfaxalone or propofol without premedication, either alfaxalone (5 mg/kg) or propofol (10 mg/kg) was administered intravenously over 120 sec in 6 cats. Each cat received the alternate treatment at least a 7-day interval. Anesthetic effects (tolerance of intubation, behavior changes and neurodepressive score) and physiological parameters were evaluated. Both treatments produced a rapid loss of consciousness, no apnea, and physiological parameters were maintained within clinically acceptable ranges apart from transient hypoxemia. The degree of hypoxemia was greater after the propofol treatment compared with the alfaxalone treatment. During the recovery period, more adverse events (ataxia, muscular tremors) were observed after the alfaxalone treatment compared with the propofol treatment.
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.20-0407