Body surface area measurements in male Hartley guinea pigs using a computed tomography scanner

The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depe...

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Bibliographic Details
Published in:Journal of Veterinary Medical Science 2021, Vol.83(1), pp.142-145
Main Authors: ITOH, Tadashi, KAWABE, Mifumi, NAGASE, Takahiko, ENDO, Katsumi, MIYOSHI, Masafumi, MIYAHARA, Kazuro
Format: Article
Language:English
Subjects:
body surface area
Body weight
Computed tomography
computed tomography (CT)
CT scanner
guinea pig
Hartley
Image processing
Laboratory Animal Science
Surface area
Tomography
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Summary:The body surface area (BSA) of animals is generally estimated by multiplying the k value (constant) by the measured body weight (BW) raised to the power of 2/3 (Meeh’s formula). Computed tomography (CT) scanners generate detailed 3-dimensional (3D) images of objects, and image analysis does not depend on operator skill. Therefore, the analysis of CT images provides accurate and reproducible BSA measurements. In this study, we measured the BSA of 25 male Hartley guinea pigs from 3 to 36 weeks of age (working BW range: 0.233 to 1.160 kg) using a CT scanner and 3D analysis software. We concluded that the k value for male Hartley guinea pigs was 8.37, based on the mean k value of the 25 animals.
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.20-0525