Celiac Disease Complicated by Rhabdomyolysis

At 37 years old, a patient developed chronic watery diarrhea, generalized pain, severe hypokalemia and elevated creatine kinase levels. She was thought to have rhabdomyolysis due to hypokalemia from chronic diarrhea. No organic cause was found. Her symptoms subsided with potassium correction, but hy...

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Bibliographic Details
Published in:Internal Medicine 2021/01/15, Vol.60(2), pp.217-222
Main Authors: Fujisawa, Mia, Matsushima, Masashi, Ueda, Takashi, Kaneko, Motoki, Fujimoto, Ryutaro, Sano, Masaya, Teramura, Erika, Monma, Makiko, Mizukami, Hajime, Nakahara, Fumio, Suzuki, Hidekazu, Suzuki, Takayoshi
Format: Article
Language:English
Subjects:
Adult
Atrophy
Case Report
Celiac disease
Celiac Disease - complications
Celiac Disease - diagnosis
Creatine
Creatine kinase
Diarrhea
Duodenum
Endoscopy
Female
Gliadin
Gluten
Humans
Hypokalemia
Immunoglobulin A
Internal medicine
Intestinal Mucosa
Intestine
Rhabdomyolysis
Rhabdomyolysis - complications
Rhabdomyolysis - diagnosis
Transglutaminase 2
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Summary:At 37 years old, a patient developed chronic watery diarrhea, generalized pain, severe hypokalemia and elevated creatine kinase levels. She was thought to have rhabdomyolysis due to hypokalemia from chronic diarrhea. No organic cause was found. Her symptoms subsided with potassium correction, but hypokalemia persisted; she visited our hospital at 44 years old. Endoscopy detected prominent atrophy of the intestinal villi. Histology indicated Marsh-Oberhuber type-3b disease. Anti-gliadin and anti-tissue transglutaminase IgA antibody tests were positive. She was diagnosed with celiac disease and started on a gluten-free diet, which improved her symptoms. This report is only the tenth of its kind worldwide.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.5358-20