The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development

Copper has demonstrated utility in multiple industrial applications for its high conductivity and antibacterial/antiviral properties. However, numerous findings have suggested potential hazards regarding pathogenesis. This study was conducted to demonstrate the application of zebrafish (Danio rerio)...

Full description

Saved in:
Bibliographic Details
Published in:BioMed research international 2021, Vol.2021 (1), p.2134928
Main Authors: Hong, Ted Inpyo, Kang, Seo-Gu, Lee, Yu-Ri, Choi, Tae-Ik, Kim, Woo-Keun, Kim, Cheol-Hee
Format: Article
Language:English
Subjects:
Analytical methods
Antiviral activity
Bioassays
Biological effects
Cell culture
Coins
Copper
Danio rerio
Drinking water
Embryogenesis
Embryonic development
Embryos
Environment
Environmental aspects
Environmental monitoring
Experiments
Health aspects
Heavy metals
Industrial applications
Larvae
Life sciences
Materials
Mortality
Organic contaminants
Pathogenesis
Phenotypes
Physiological aspects
Pollution detection
Pollution effects
Toxicity
Water monitoring
Water pollution
Water quality
Zebra fish
Zebrafish
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c461t-362026ebe9d4c264cc56b5f5ee9f2ac13d826aef5fc31e2f7c1601946f24068e3
container_end_page
container_issue 1
container_start_page 2134928
container_title BioMed research international
container_volume 2021
creator Hong, Ted Inpyo
Kang, Seo-Gu
Lee, Yu-Ri
Choi, Tae-Ik
Kim, Woo-Keun
Kim, Cheol-Hee
description Copper has demonstrated utility in multiple industrial applications for its high conductivity and antibacterial/antiviral properties. However, numerous findings have suggested potential hazards regarding pathogenesis. This study was conducted to demonstrate the application of zebrafish (Danio rerio) as a cost-effective biological assay to detect environmental pollution, i.e., heavy metal of coins. We demonstrated that zebrafish larvae exposed to copper-plated coins or copper (II) ion solution elicited a consistent phenotype of early mortality without signs of morphological defects in surviving individuals. Copper ion solution served as a standard to (1) corroborate copper exposure from coins and (2) demonstrate proportional increase in early mortality phenotype according to concentration. We found that 5 μM CuSO4·5H2O was the minimal concentration to elicit the observed phenotypes from copper toxicity. This study aimed to demonstrate how a simple protocol involving wild-type zebrafish larvae could provide an economical solution to water monitoring in areas of rapid technological advancement and increasing environmental concerns, especially in communities without access to expensive analytical methods.
doi_str_mv 10.1155/2021/2134928
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7880709</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A683531059</galeid><sourcerecordid>A683531059</sourcerecordid><originalsourceid>FETCH-LOGICAL-c461t-362026ebe9d4c264cc56b5f5ee9f2ac13d826aef5fc31e2f7c1601946f24068e3</originalsourceid><addsrcrecordid>eNp9kUtPGzEUha2KqiDKrms0Upc0xe-xN0gopA8JqRvYdGN5nGtilLEHewaUf19HSUO7wZtr2Z_PPdcHoU8EfyVEiEuKKbmkhHFN1Tt0QhnhM0k4OTrsGTtGZ6U84roUkVjLD-iYMUlV24oTdH-3gmbhPbixNMk38zQMkGuJZQzjBHHcnYbYzKecIbpNk2Kz6Lu8STG45jd02fpQVs0NPMM6DX198xG993Zd4GxfT9H9t8Xd_Mfs9tf3n_Pr25njkoyz6gJTCR3oJXdUcueE7IQXANpT6whbKioteOEdI0B96-oARHPpKcdSATtFVzvdYep6WLraOtu1GXLobd6YZIP5_yaGlXlIz6ZVCrdYV4HPe4GcniYoo3lMU47Vs6FcaYLblvFX6sGuwYToUxVzfSjOXEsttdCifvSblGKCESy2Hb_sKJdTKRn8wS3BZpup2WZq9plW_PzfCQ_w3wQrcLEDViEu7Ut4W-4PbZSm-w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2489107734</pqid></control><display><type>article</type><title>The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development</title><source>Wiley Online Library</source><source>Publicly Available Content (ProQuest)</source><creator>Hong, Ted Inpyo ; Kang, Seo-Gu ; Lee, Yu-Ri ; Choi, Tae-Ik ; Kim, Woo-Keun ; Kim, Cheol-Hee</creator><contributor>Fierascu, Radu Claudiu</contributor><creatorcontrib>Hong, Ted Inpyo ; Kang, Seo-Gu ; Lee, Yu-Ri ; Choi, Tae-Ik ; Kim, Woo-Keun ; Kim, Cheol-Hee ; Fierascu, Radu Claudiu</creatorcontrib><description>Copper has demonstrated utility in multiple industrial applications for its high conductivity and antibacterial/antiviral properties. However, numerous findings have suggested potential hazards regarding pathogenesis. This study was conducted to demonstrate the application of zebrafish (Danio rerio) as a cost-effective biological assay to detect environmental pollution, i.e., heavy metal of coins. We demonstrated that zebrafish larvae exposed to copper-plated coins or copper (II) ion solution elicited a consistent phenotype of early mortality without signs of morphological defects in surviving individuals. Copper ion solution served as a standard to (1) corroborate copper exposure from coins and (2) demonstrate proportional increase in early mortality phenotype according to concentration. We found that 5 μM CuSO4·5H2O was the minimal concentration to elicit the observed phenotypes from copper toxicity. This study aimed to demonstrate how a simple protocol involving wild-type zebrafish larvae could provide an economical solution to water monitoring in areas of rapid technological advancement and increasing environmental concerns, especially in communities without access to expensive analytical methods.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2021/2134928</identifier><identifier>PMID: 33628775</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Analytical methods ; Antiviral activity ; Bioassays ; Biological effects ; Cell culture ; Coins ; Copper ; Danio rerio ; Drinking water ; Embryogenesis ; Embryonic development ; Embryos ; Environment ; Environmental aspects ; Environmental monitoring ; Experiments ; Health aspects ; Heavy metals ; Industrial applications ; Larvae ; Life sciences ; Materials ; Mortality ; Organic contaminants ; Pathogenesis ; Phenotypes ; Physiological aspects ; Pollution detection ; Pollution effects ; Toxicity ; Water monitoring ; Water pollution ; Water quality ; Zebra fish ; Zebrafish</subject><ispartof>BioMed research international, 2021, Vol.2021 (1), p.2134928</ispartof><rights>Copyright © 2021 Ted Inpyo Hong et al.</rights><rights>COPYRIGHT 2021 John Wiley &amp; Sons, Inc.</rights><rights>Copyright © 2021 Ted Inpyo Hong et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2021 Ted Inpyo Hong et al. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c461t-362026ebe9d4c264cc56b5f5ee9f2ac13d826aef5fc31e2f7c1601946f24068e3</cites><orcidid>0000-0002-3019-0699</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2489107734/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2489107734?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,4010,25731,27900,27901,27902,36989,44566,74869</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33628775$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Fierascu, Radu Claudiu</contributor><creatorcontrib>Hong, Ted Inpyo</creatorcontrib><creatorcontrib>Kang, Seo-Gu</creatorcontrib><creatorcontrib>Lee, Yu-Ri</creatorcontrib><creatorcontrib>Choi, Tae-Ik</creatorcontrib><creatorcontrib>Kim, Woo-Keun</creatorcontrib><creatorcontrib>Kim, Cheol-Hee</creatorcontrib><title>The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>Copper has demonstrated utility in multiple industrial applications for its high conductivity and antibacterial/antiviral properties. However, numerous findings have suggested potential hazards regarding pathogenesis. This study was conducted to demonstrate the application of zebrafish (Danio rerio) as a cost-effective biological assay to detect environmental pollution, i.e., heavy metal of coins. We demonstrated that zebrafish larvae exposed to copper-plated coins or copper (II) ion solution elicited a consistent phenotype of early mortality without signs of morphological defects in surviving individuals. Copper ion solution served as a standard to (1) corroborate copper exposure from coins and (2) demonstrate proportional increase in early mortality phenotype according to concentration. We found that 5 μM CuSO4·5H2O was the minimal concentration to elicit the observed phenotypes from copper toxicity. This study aimed to demonstrate how a simple protocol involving wild-type zebrafish larvae could provide an economical solution to water monitoring in areas of rapid technological advancement and increasing environmental concerns, especially in communities without access to expensive analytical methods.</description><subject>Analytical methods</subject><subject>Antiviral activity</subject><subject>Bioassays</subject><subject>Biological effects</subject><subject>Cell culture</subject><subject>Coins</subject><subject>Copper</subject><subject>Danio rerio</subject><subject>Drinking water</subject><subject>Embryogenesis</subject><subject>Embryonic development</subject><subject>Embryos</subject><subject>Environment</subject><subject>Environmental aspects</subject><subject>Environmental monitoring</subject><subject>Experiments</subject><subject>Health aspects</subject><subject>Heavy metals</subject><subject>Industrial applications</subject><subject>Larvae</subject><subject>Life sciences</subject><subject>Materials</subject><subject>Mortality</subject><subject>Organic contaminants</subject><subject>Pathogenesis</subject><subject>Phenotypes</subject><subject>Physiological aspects</subject><subject>Pollution detection</subject><subject>Pollution effects</subject><subject>Toxicity</subject><subject>Water monitoring</subject><subject>Water pollution</subject><subject>Water quality</subject><subject>Zebra fish</subject><subject>Zebrafish</subject><issn>2314-6133</issn><issn>2314-6141</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNp9kUtPGzEUha2KqiDKrms0Upc0xe-xN0gopA8JqRvYdGN5nGtilLEHewaUf19HSUO7wZtr2Z_PPdcHoU8EfyVEiEuKKbmkhHFN1Tt0QhnhM0k4OTrsGTtGZ6U84roUkVjLD-iYMUlV24oTdH-3gmbhPbixNMk38zQMkGuJZQzjBHHcnYbYzKecIbpNk2Kz6Lu8STG45jd02fpQVs0NPMM6DX198xG993Zd4GxfT9H9t8Xd_Mfs9tf3n_Pr25njkoyz6gJTCR3oJXdUcueE7IQXANpT6whbKioteOEdI0B96-oARHPpKcdSATtFVzvdYep6WLraOtu1GXLobd6YZIP5_yaGlXlIz6ZVCrdYV4HPe4GcniYoo3lMU47Vs6FcaYLblvFX6sGuwYToUxVzfSjOXEsttdCifvSblGKCESy2Hb_sKJdTKRn8wS3BZpup2WZq9plW_PzfCQ_w3wQrcLEDViEu7Ut4W-4PbZSm-w</recordid><startdate>2021</startdate><enddate>2021</enddate><creator>Hong, Ted Inpyo</creator><creator>Kang, Seo-Gu</creator><creator>Lee, Yu-Ri</creator><creator>Choi, Tae-Ik</creator><creator>Kim, Woo-Keun</creator><creator>Kim, Cheol-Hee</creator><general>Hindawi</general><general>John Wiley &amp; Sons, Inc</general><general>Hindawi Limited</general><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3019-0699</orcidid></search><sort><creationdate>2021</creationdate><title>The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development</title><author>Hong, Ted Inpyo ; Kang, Seo-Gu ; Lee, Yu-Ri ; Choi, Tae-Ik ; Kim, Woo-Keun ; Kim, Cheol-Hee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-362026ebe9d4c264cc56b5f5ee9f2ac13d826aef5fc31e2f7c1601946f24068e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Analytical methods</topic><topic>Antiviral activity</topic><topic>Bioassays</topic><topic>Biological effects</topic><topic>Cell culture</topic><topic>Coins</topic><topic>Copper</topic><topic>Danio rerio</topic><topic>Drinking water</topic><topic>Embryogenesis</topic><topic>Embryonic development</topic><topic>Embryos</topic><topic>Environment</topic><topic>Environmental aspects</topic><topic>Environmental monitoring</topic><topic>Experiments</topic><topic>Health aspects</topic><topic>Heavy metals</topic><topic>Industrial applications</topic><topic>Larvae</topic><topic>Life sciences</topic><topic>Materials</topic><topic>Mortality</topic><topic>Organic contaminants</topic><topic>Pathogenesis</topic><topic>Phenotypes</topic><topic>Physiological aspects</topic><topic>Pollution detection</topic><topic>Pollution effects</topic><topic>Toxicity</topic><topic>Water monitoring</topic><topic>Water pollution</topic><topic>Water quality</topic><topic>Zebra fish</topic><topic>Zebrafish</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hong, Ted Inpyo</creatorcontrib><creatorcontrib>Kang, Seo-Gu</creatorcontrib><creatorcontrib>Lee, Yu-Ri</creatorcontrib><creatorcontrib>Choi, Tae-Ik</creatorcontrib><creatorcontrib>Kim, Woo-Keun</creatorcontrib><creatorcontrib>Kim, Cheol-Hee</creatorcontrib><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Middle East &amp; Africa Database</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest advanced technologies &amp; aerospace journals</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BioMed research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hong, Ted Inpyo</au><au>Kang, Seo-Gu</au><au>Lee, Yu-Ri</au><au>Choi, Tae-Ik</au><au>Kim, Woo-Keun</au><au>Kim, Cheol-Hee</au><au>Fierascu, Radu Claudiu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2021</date><risdate>2021</risdate><volume>2021</volume><issue>1</issue><spage>2134928</spage><pages>2134928-</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>Copper has demonstrated utility in multiple industrial applications for its high conductivity and antibacterial/antiviral properties. However, numerous findings have suggested potential hazards regarding pathogenesis. This study was conducted to demonstrate the application of zebrafish (Danio rerio) as a cost-effective biological assay to detect environmental pollution, i.e., heavy metal of coins. We demonstrated that zebrafish larvae exposed to copper-plated coins or copper (II) ion solution elicited a consistent phenotype of early mortality without signs of morphological defects in surviving individuals. Copper ion solution served as a standard to (1) corroborate copper exposure from coins and (2) demonstrate proportional increase in early mortality phenotype according to concentration. We found that 5 μM CuSO4·5H2O was the minimal concentration to elicit the observed phenotypes from copper toxicity. This study aimed to demonstrate how a simple protocol involving wild-type zebrafish larvae could provide an economical solution to water monitoring in areas of rapid technological advancement and increasing environmental concerns, especially in communities without access to expensive analytical methods.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>33628775</pmid><doi>10.1155/2021/2134928</doi><orcidid>https://orcid.org/0000-0002-3019-0699</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2314-6133
ispartof BioMed research international, 2021, Vol.2021 (1), p.2134928
issn 2314-6133
2314-6141
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7880709
source Wiley Online Library; Publicly Available Content (ProQuest)
subjects Analytical methods
Antiviral activity
Bioassays
Biological effects
Cell culture
Coins
Copper
Danio rerio
Drinking water
Embryogenesis
Embryonic development
Embryos
Environment
Environmental aspects
Environmental monitoring
Experiments
Health aspects
Heavy metals
Industrial applications
Larvae
Life sciences
Materials
Mortality
Organic contaminants
Pathogenesis
Phenotypes
Physiological aspects
Pollution detection
Pollution effects
Toxicity
Water monitoring
Water pollution
Water quality
Zebra fish
Zebrafish
title The Effects of Copper Constituent of Coin Currency on Embryonic Zebrafish Development
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T13%3A23%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Effects%20of%20Copper%20Constituent%20of%20Coin%20Currency%20on%20Embryonic%20Zebrafish%20Development&rft.jtitle=BioMed%20research%20international&rft.au=Hong,%20Ted%20Inpyo&rft.date=2021&rft.volume=2021&rft.issue=1&rft.spage=2134928&rft.pages=2134928-&rft.issn=2314-6133&rft.eissn=2314-6141&rft_id=info:doi/10.1155/2021/2134928&rft_dat=%3Cgale_pubme%3EA683531059%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c461t-362026ebe9d4c264cc56b5f5ee9f2ac13d826aef5fc31e2f7c1601946f24068e3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2489107734&rft_id=info:pmid/33628775&rft_galeid=A683531059&rfr_iscdi=true