Failure to Detect Viral RNA in Follicular Fluid Aspirates from a SARS-CoV-2-Positive Woman

Although there is no known difference between the clinical manifestations of SARS-CoV-2 in pregnant and non-pregnant women based on the studies published until now, in vitro fertilization (IVF) treatments were suspended during the pandemic due to uncertainties with the suggestions of associated soci...

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Bibliographic Details
Published in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2021-08, Vol.28 (8), p.2144-2146
Main Authors: Demirel, Cem, Tulek, Firat, Celik, Hale Goksever, Donmez, Ersan, Tuysuz, Gulsum, Gökcan, Bilgi
Format: Article
Language:English
Subjects:
Adult
COVID-19 - diagnosis
COVID-19 - virology
COVID-19 Nucleic Acid Testing
Embryology
Female
Follicular Fluid - virology
Humans
Infertility, Female - diagnosis
Infertility, Female - physiopathology
Infertility, Female - therapy
Infertility: Case Study
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Oocyte Retrieval
Predictive Value of Tests
Reproductive Medicine
RNA, Viral - genetics
SARS-CoV-2 - genetics
Sperm Injections, Intracytoplasmic
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Summary:Although there is no known difference between the clinical manifestations of SARS-CoV-2 in pregnant and non-pregnant women based on the studies published until now, in vitro fertilization (IVF) treatments were suspended during the pandemic due to uncertainties with the suggestions of associated societies. However, we do not have enough data on the exact effects of SARS-CoV-2 on fertility and pregnancy and whether there are damaging effects on IVF outcome. There is no available evidence about the transmission of SARS-CoV-2 by either sexual way or through intrauterine insemination (IUI) or IVF. Up until now, there is no report to document the presence or absence of viral RNA in follicular fluid of SARS-CoV-2-positive women. In this paper, we present a case of oocyte retrieval from a SARS-CoV-2-positive woman and the search for viral RNA by polymerase chain reaction (PCR) in the follicular fluid aspirates.
ISSN:1933-7191
1933-7205
DOI:10.1007/s43032-021-00502-9