Clinical characteristics and prognosis of elderly patients with colorectal cancer: Comparison between surgical resection and supportive care

Elderly colorectal cancer (CRC) patients tend to avoid standard treatment, especially curative surgical resection, because of concerns about surgical complications or underlying diseases. This study is intended to compare clinical characteristics and prognosis between patients who had undergone surg...

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Bibliographic Details
Published in:Medicine (Baltimore) 2021-02, Vol.100 (7), p.e24609-e24609
Main Authors: Kim, Soohwan, Kim, Dong Suk, Soh, Jae Seung, Lim, Sang-Woo, Lim, Hyun, Kang, Ho Suk, Kim, Jong Hyeok
Format: Article
Language:English
Subjects:
Aged, 80 and over
Colorectal Neoplasms - mortality
Colorectal Neoplasms - surgery
Colorectal Neoplasms - therapy
Conservative Treatment
Female
Humans
Male
Observational Study
Prognosis
Republic of Korea
Retrospective Studies
Survival Analysis
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Summary:Elderly colorectal cancer (CRC) patients tend to avoid standard treatment, especially curative surgical resection, because of concerns about surgical complications or underlying diseases. This study is intended to compare clinical characteristics and prognosis between patients who had undergone surgical resection and received supportive care, and to evaluate the usefulness of surgical treatment in elderly patients.A total of 114 patients aged ≥80 years who were diagnosed with CRC were analyzed retrospectively. Of these patients, 73 patients underwent surgical resection for malignancy and 41 patients received supportive care. Clinicopathological factors and overall survival (OS) rates were compared.The surgical resection group had better Eastern Cooperative Oncology Group performance status, American Society of Anesthesiologists (ASA) physical status, and a lower stage than did the supportive-care group. The 3-year OS rate of the surgical group was significantly higher than that of the supportive-care group (60.7% vs 9.1%, P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000024609