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Is the axial length a risk factor for post-LASIK myopic regression?

Purpose To assess the relationship between the axial length and post-LASIK regression in myopic patients. Methods This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2...

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Published in:Graefe's archive for clinical and experimental ophthalmology 2021-03, Vol.259 (3), p.777-786
Main Author: Gab-Alla, Amr A.
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description Purpose To assess the relationship between the axial length and post-LASIK regression in myopic patients. Methods This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG). Results This study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was − 4.3 ± 2.1D, range (− 0.50 to − 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) ( t test statistic = 69.3; P value
doi_str_mv 10.1007/s00417-020-04990-4
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Methods This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG). Results This study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was − 4.3 ± 2.1D, range (− 0.50 to − 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) ( t test statistic = 69.3; P value &lt; 0.001). Conclusions Pre-operative high axial length increases the risk of myopic regression after LASIK.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/s00417-020-04990-4</identifier><identifier>PMID: 33128672</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Medical records ; Medicine ; Medicine &amp; Public Health ; Myopia ; Ophthalmology ; Patients ; Refractive Surgery ; Risk factors</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 2021-03, Vol.259 (3), p.777-786</ispartof><rights>The Author(s) 2020</rights><rights>The Author(s) 2020. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-80dccd8e8e947d993cb398c87388090931997c59388f856750d5aaf97ce03a3a3</citedby><cites>FETCH-LOGICAL-c474t-80dccd8e8e947d993cb398c87388090931997c59388f856750d5aaf97ce03a3a3</cites><orcidid>0000-0002-8005-8178</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33128672$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gab-Alla, Amr A.</creatorcontrib><title>Is the axial length a risk factor for post-LASIK myopic regression?</title><title>Graefe's archive for clinical and experimental ophthalmology</title><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><description>Purpose To assess the relationship between the axial length and post-LASIK regression in myopic patients. Methods This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG). Results This study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was − 4.3 ± 2.1D, range (− 0.50 to − 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) ( t test statistic = 69.3; P value &lt; 0.001). Conclusions Pre-operative high axial length increases the risk of myopic regression after LASIK.</description><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Myopia</subject><subject>Ophthalmology</subject><subject>Patients</subject><subject>Refractive Surgery</subject><subject>Risk factors</subject><issn>0721-832X</issn><issn>1435-702X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kU1PGzEQhq2qqITQP8ABWeqlF8P4Y2P7UoQiPiIicYBK3CzH600WNuvU3lTk3-MQCB8HZFmWZ555PeMXoQMKRxRAHicAQSUBBgSE1kDEN9SjghdEArv7jnogGSWKs7tdtJfSPWSeF_QH2uWcMjWQrIeGo4S7mcf2sbYNbnw77WbY4linB1xZ14WIq7wXIXVkfHozusLzVVjUDkc_jT6lOrQn-2insk3yP1_OPvp7fnY7vCTj64vR8HRMnJCiIwpK50rllddCllpzN-FaOSW5UqBBc6q1dIXO10oVA1lAWVhb5ZgHbvPqoz8b3cVyMvel820XbWMWsZ7buDLB1uZjpq1nZhr-G6lBSMqywO8XgRj-LX3qzLxOzjeNbX1YJsNEMRBUaKky-usTeh-Wsc3jZUozqSXkn-4jtqFcDClFX22boWDWHpmNRyZ7ZJ49Muuiw_djbEteTckA3wApp9qpj29vfyH7BNBNm0k</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Gab-Alla, Amr A.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8005-8178</orcidid></search><sort><creationdate>20210301</creationdate><title>Is the axial length a risk factor for post-LASIK myopic regression?</title><author>Gab-Alla, Amr A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-80dccd8e8e947d993cb398c87388090931997c59388f856750d5aaf97ce03a3a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine &amp; Public Health</topic><topic>Myopia</topic><topic>Ophthalmology</topic><topic>Patients</topic><topic>Refractive Surgery</topic><topic>Risk factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gab-Alla, Amr A.</creatorcontrib><collection>Springer Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gab-Alla, Amr A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is the axial length a risk factor for post-LASIK myopic regression?</atitle><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle><stitle>Graefes Arch Clin Exp Ophthalmol</stitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><date>2021-03-01</date><risdate>2021</risdate><volume>259</volume><issue>3</issue><spage>777</spage><epage>786</epage><pages>777-786</pages><issn>0721-832X</issn><eissn>1435-702X</eissn><abstract>Purpose To assess the relationship between the axial length and post-LASIK regression in myopic patients. Methods This is a retrospective case series study conducted at a private eye centre, Ismailia, Egypt. The clinical records of the patients, who experienced LASIK to correct myopia from January 2016 to January 2018, were analysed for myopic regression. The patients were operated on, examined, and followed-up 1 year by one surgeon (AAG). Results This study included 1219 patients (2316 eyes) with myopia. Mean ± SD of pre-operative spherical equivalent (SE) was − 4.3 ± 2.1D, range (− 0.50 to − 10.0D). Mean ± SD age of the patients was 26.4 ± 6.8 years, range (21 to 50 years). Male to female ratio was 30.5 to 69.5%. The cumulative incidence rate of myopic regression according to the medical records of the patients was 25.12% (582 eyes out of total 2316 eyes) along the 2 years of this study (12.6% per year). Of the total patients, 14.94% had pre-operative high myopia, 35.84% had pre-operative moderate myopia, and 49.2% had pre-operative low myopia. Of the patients with myopic regression, 52.6% had pre-operative high myopia, 34% had pre-operative moderate myopia, and 13.4% had pre-operative low myopia. The mean ± SD of the axial length of the patients with myopic regression was 26.6 ± 0.44 mm, range (26.0 to 27.86 mm), while the mean ± SD of the axial length of other patients with stable refraction was 24.38 ± 0.73 mm, range (22.9 to 25.9 mm) ( t test statistic = 69.3; P value &lt; 0.001). Conclusions Pre-operative high axial length increases the risk of myopic regression after LASIK.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>33128672</pmid><doi>10.1007/s00417-020-04990-4</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-8005-8178</orcidid><oa>free_for_read</oa></addata></record>
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subjects Medical records
Medicine
Medicine & Public Health
Myopia
Ophthalmology
Patients
Refractive Surgery
Risk factors
title Is the axial length a risk factor for post-LASIK myopic regression?
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