Preliminary Study on the Effect of an Early Physical Therapy Intervention after Sentinel Lymph Node Biopsy: A Multicenter Non-Randomized Controlled Trial

• Published in: International journal of environmental research and public health 2021-01, Vol.18 (3), p.1275
• Main Authors: Muñoz-Fernández, María Jesús, Medrano-Sánchez, Esther M, Ostos-Díaz, Beatriz, Martín-Valero, Rocío, Suárez-Serrano, Carmen, Casuso-Holgado, María Jesús
• Format: Article
• Language: English
• Subjects: Axilla; Biopsy; Breast cancer; Breast Neoplasms - surgery; Cancer surgery; Clinical trials; Dissection; Female; Grip strength; Hospitals; Humans; Intervention; Lymph Node Excision; Lymph nodes; Lymphatic system; Lymphedema; Mastectomy; Minimally invasive surgery; Pain; Patients; Physical therapy; Physical Therapy Modalities; Quality of Life; Range of motion; Scars; Sentinel Lymph Node Biopsy
• ISSN: 1660-4601; 1661-7827; 1660-4601
• DOI: 10.3390/ijerph18031275

Selective sentinel lymph node biopsy (SLNB) represents a minimally invasive surgery in patients with breast cancer. The purpose of this study was to explore the possible effect of an early physiotherapy intervention for the recovery of the upper limb and the surgical scars after SLNB in comparison with usual care. A total of 40 patients were enrolled in either the control group ( = 20) or the experimental group ( = 20). The intervention group performed an early physiotherapy program based on functional exercises, scar manual therapy, and educational tips. The control group received usual care. Shoulder range of motion (ROM), grip strength, upper limb pain and disability (SPADI), scar recovery (POSAS), myofascial adhesions (MAP-BC), quality of life (EORTCQLA-BR-23) and the presence of axillary web syndrome (AWS) and lymphoedema were assessed at baseline and immediately after intervention. A follow-up period of 6 months was performed for lymphoedema surveillance. Between groups significant differences in favor of the intervention were found for ROM (r = 0.43), grip strength (r = 0.32), SPADI (d = 0.45), POSAS (d = 1.28), MAP-BC (d = 1.82) and EORTCQLQ-BR 23 general function subscale (d = 0.37) ( < 0.05 for all variables). Our results suggest that an early physical therapy program seems to be more effective than usual care in women after SLNB. However, results should be interpreted with caution and future randomized trial with a larger sample size is needed.