Loading…

Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia

Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2021-01, Vol.13 (1), p.e12959
Main Authors: Fasulo, Sydney M, Narvaneni, Spandana, Kumar, Vinod, Manje Gowda, Anusha, Sultana, Yasmeen
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c271t-4c3a743a8ff73930c1df04f80bf7385a0a42198ce9a5ce98d19e34f011c7cd2b3
container_end_page
container_issue 1
container_start_page e12959
container_title Curēus (Palo Alto, CA)
container_volume 13
creator Fasulo, Sydney M
Narvaneni, Spandana
Kumar, Vinod
Manje Gowda, Anusha
Sultana, Yasmeen
description Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL.
doi_str_mv 10.7759/cureus.12959
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7920237</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2497112951</sourcerecordid><originalsourceid>FETCH-LOGICAL-c271t-4c3a743a8ff73930c1df04f80bf7385a0a42198ce9a5ce98d19e34f011c7cd2b3</originalsourceid><addsrcrecordid>eNpVkE1PAyEQhonR2Kb25tlw9OBWPnYLeDCpjVqTTfRgz4SyrKLbpcJi0n8vtbWpF2AyT94ZHgDOMRoxVohrHb2JYYSJKMQR6BM85hnHPD8-ePfAMIQPhBBGjCCGTkGP0nEhMM77YFKuO6vhnWsNLE2wrr2BkxbO2xiiauCLN8G0nepSA7oazpT1azg1TZPo-GmWVp2Bk1o1wQx39wDMH-5fp7OsfH58mk7KTBOGuyzXVLGcKl7XjAqKNK5qlNccLVLNC4VUTrDg2ghVpINXWBia1whjzXRFFnQAbre5q7hYmkqntbxq5MrbpfJr6ZSV_zutfZdv7lsyQRChLAVc7gK8-4omdHJpg05fUa1xMUiSC4Y3JnFCr7ao9i4Eb-r9GIzkRrzcipe_4hN-cbjaHv7TTH8A_1d_zQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2497112951</pqid></control><display><type>article</type><title>Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia</title><source>Open Access: PubMed Central</source><source>ProQuest - Publicly Available Content Database</source><creator>Fasulo, Sydney M ; Narvaneni, Spandana ; Kumar, Vinod ; Manje Gowda, Anusha ; Sultana, Yasmeen</creator><creatorcontrib>Fasulo, Sydney M ; Narvaneni, Spandana ; Kumar, Vinod ; Manje Gowda, Anusha ; Sultana, Yasmeen</creatorcontrib><description>Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.12959</identifier><identifier>PMID: 33659114</identifier><language>eng</language><publisher>United States: Cureus</publisher><subject>Hematology ; Oncology ; Radiology</subject><ispartof>Curēus (Palo Alto, CA), 2021-01, Vol.13 (1), p.e12959</ispartof><rights>Copyright © 2021, Fasulo et al.</rights><rights>Copyright © 2021, Fasulo et al. 2021 Fasulo et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c271t-4c3a743a8ff73930c1df04f80bf7385a0a42198ce9a5ce98d19e34f011c7cd2b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920237/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920237/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33659114$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fasulo, Sydney M</creatorcontrib><creatorcontrib>Narvaneni, Spandana</creatorcontrib><creatorcontrib>Kumar, Vinod</creatorcontrib><creatorcontrib>Manje Gowda, Anusha</creatorcontrib><creatorcontrib>Sultana, Yasmeen</creatorcontrib><title>Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL.</description><subject>Hematology</subject><subject>Oncology</subject><subject>Radiology</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNpVkE1PAyEQhonR2Kb25tlw9OBWPnYLeDCpjVqTTfRgz4SyrKLbpcJi0n8vtbWpF2AyT94ZHgDOMRoxVohrHb2JYYSJKMQR6BM85hnHPD8-ePfAMIQPhBBGjCCGTkGP0nEhMM77YFKuO6vhnWsNLE2wrr2BkxbO2xiiauCLN8G0nepSA7oazpT1azg1TZPo-GmWVp2Bk1o1wQx39wDMH-5fp7OsfH58mk7KTBOGuyzXVLGcKl7XjAqKNK5qlNccLVLNC4VUTrDg2ghVpINXWBia1whjzXRFFnQAbre5q7hYmkqntbxq5MrbpfJr6ZSV_zutfZdv7lsyQRChLAVc7gK8-4omdHJpg05fUa1xMUiSC4Y3JnFCr7ao9i4Eb-r9GIzkRrzcipe_4hN-cbjaHv7TTH8A_1d_zQ</recordid><startdate>20210128</startdate><enddate>20210128</enddate><creator>Fasulo, Sydney M</creator><creator>Narvaneni, Spandana</creator><creator>Kumar, Vinod</creator><creator>Manje Gowda, Anusha</creator><creator>Sultana, Yasmeen</creator><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20210128</creationdate><title>Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia</title><author>Fasulo, Sydney M ; Narvaneni, Spandana ; Kumar, Vinod ; Manje Gowda, Anusha ; Sultana, Yasmeen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c271t-4c3a743a8ff73930c1df04f80bf7385a0a42198ce9a5ce98d19e34f011c7cd2b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Hematology</topic><topic>Oncology</topic><topic>Radiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fasulo, Sydney M</creatorcontrib><creatorcontrib>Narvaneni, Spandana</creatorcontrib><creatorcontrib>Kumar, Vinod</creatorcontrib><creatorcontrib>Manje Gowda, Anusha</creatorcontrib><creatorcontrib>Sultana, Yasmeen</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fasulo, Sydney M</au><au>Narvaneni, Spandana</au><au>Kumar, Vinod</au><au>Manje Gowda, Anusha</au><au>Sultana, Yasmeen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2021-01-28</date><risdate>2021</risdate><volume>13</volume><issue>1</issue><spage>e12959</spage><pages>e12959-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL.</abstract><cop>United States</cop><pub>Cureus</pub><pmid>33659114</pmid><doi>10.7759/cureus.12959</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2021-01, Vol.13 (1), p.e12959
issn 2168-8184
2168-8184
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7920237
source Open Access: PubMed Central; ProQuest - Publicly Available Content Database
subjects Hematology
Oncology
Radiology
title Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T04%3A28%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lytic%20Bone%20Lesion:%20An%20Unusual%20Presentation%20of%20Hairy%20Cell%20Leukemia&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Fasulo,%20Sydney%20M&rft.date=2021-01-28&rft.volume=13&rft.issue=1&rft.spage=e12959&rft.pages=e12959-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.12959&rft_dat=%3Cproquest_pubme%3E2497112951%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c271t-4c3a743a8ff73930c1df04f80bf7385a0a42198ce9a5ce98d19e34f011c7cd2b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2497112951&rft_id=info:pmid/33659114&rfr_iscdi=true