Development of Multifunctional Materials Based on Poly(ether ether ketone) with Improved Biological Performances for Dental Applications

The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and...

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Bibliographic Details
Published in:Materials 2021-02, Vol.14 (4), p.1047
Main Authors: Montaño-Machado, Vanessa, Chevallier, Pascale, Bonilla-Gameros, Linda, Copes, Francesco, Quarta, Chiara, Kú-Herrera, José de Jesús, Soriano, Florentino, Padilla-Gainza, Victoria, Morales, Graciela, Mantovani, Diego
Format: Article
Language:English
Subjects:
Bacterial diseases
Biomedical materials
Contact angle
Dental implants
Dental materials
Dentistry
Differential scanning calorimetry
Mechanical properties
Multifunctional materials
Nanoparticles
Osteoblasts
Polyether ether ketones
Scanning electron microscopy
Surgical implants
Thermal stability
Thermogravimetric analysis
Titanium
Transmission electron microscopy
Zinc oxide
Zinc oxides
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Summary:The main target for the future of materials in dentistry aims to develop dental implants that will have optimal integration with the surrounding tissues, while preventing or avoiding bacterial infections. In this project, poly(ether ether ketone) (PEEK), known for its suitable biocompa-tibility and mechanical properties for dental applications, was loaded with 1, 3, and 5 wt.% ZnO nanoparticles to provide antibacterial properties and improve interaction with cells. Sample cha-racterization by X-ray diffraction (XRD), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) as well as mechanical properties showed the presence of the nanoparticles and their effect in PEEK matrices, preserving their relevant properties for dental applications. Al-though, the incorporation of ZnO nanoparticles did not improve the mechanical properties and a slight decrease in the thermal stability of the materials was observed. Hemocompatibility and osteoblasts-like cell viability tests showed improved biological performances when ZnO was present, demonstrating high potential for dental implant applications.
ISSN:1996-1944
1996-1944
DOI:10.3390/ma14041047