An Irreversible Worsening Cardiac Function after Withdrawing Medical Treatments in a Patient with Dilated Cardiomyopathy: A Pathological Analysis

A 44-year-old man diagnosed with idiopathic dilated cardiomyopathy was admitted to our hospital with acute decompensated heart failure. Seven years before this admission, the first introduction of medication resulted in left ventricular (LV) recovery, which was sustained for several years. However,...

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Bibliographic Details
Published in:Internal Medicine 2021/02/15, Vol.60(4), pp.553-556
Main Authors: Yazaki, Mayu, Nabeta, Takeru, Inomata, Takayuki, Ako, Junya
Format: Article
Language:English
Subjects:
Adult
beta-blocker
Biopsy
cardiac fibrosis
Cardiomyopathy
Cardiomyopathy, Dilated - drug therapy
Case Report
Congestive heart failure
Dilated cardiomyopathy
Fibrosis
Heart Failure - drug therapy
Heart Failure - etiology
Humans
Internal medicine
Magnetic Resonance Imaging
Male
Medical treatment
Myocardium
Patients
renin-angiotensin-aldosterone system inhibitors
Ventricle
Ventricular Function, Left
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Summary:A 44-year-old man diagnosed with idiopathic dilated cardiomyopathy was admitted to our hospital with acute decompensated heart failure. Seven years before this admission, the first introduction of medication resulted in left ventricular (LV) recovery, which was sustained for several years. However, the patient stopped taking his medication, resulting in worsening of the LV function. Despite the second introduction of medication, the LV function did not improve. We performed cardiac magnetic resonance imaging and an endomyocardial biopsy, which revealed the significant development of cardiac fibrosis that had not been present at the time of the initial diagnosis.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.5150-20