Science supporting negative pressure wound therapy with instillation

A new method (V.A.C.ULTA™ Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C.® Therapy, KCI USA, Inc.) with regulated, periodic instillation of user‐selected topical wound solutions (V.A.C. VeraFlo™ Therapy, KCI USA, Inc.). In simula...

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Bibliographic Details
Published in:International wound journal 2013-12, Vol.10 (s1), p.20-24
Main Authors: Rycerz, Anthony M, Allen, Diwi, Lessing, M Christian
Format: Article
Language:English
Subjects:
Animals
Anti-Infective Agents, Local - therapeutic use
Bandages
Cross Infection - prevention & control
Equipment Design
Granulation Tissue - physiology
Humans
Negative pressure wound therapy
Negative pressure wound therapy with instillation
Negative-Pressure Wound Therapy - instrumentation
Negative-Pressure Wound Therapy - methods
Periodic instillation
Reticulated open-cell foam
Review
Therapeutic Irrigation
Wound cleansing
Wound Healing - physiology
Wound Infection - prevention & control
Wounds and Injuries - therapy
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Summary:A new method (V.A.C.ULTA™ Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C.® Therapy, KCI USA, Inc.) with regulated, periodic instillation of user‐selected topical wound solutions (V.A.C. VeraFlo™ Therapy, KCI USA, Inc.). In simulated wound model studies comparing solution distribution using NPWT with and without a soak phase, the instillation soak phase allowed for uniform solution distribution across the wound bed, whereas continuous (no soak) irrigation resulted in uneven coverage. Additional in vitro work illustrated that bacterial particle aerosolisation during wound cleansing was significantly decreased using NPWT with instillation (NPWTi) versus commercially available low‐pressure wound cleansers (P 
ISSN:1742-4801
1742-481X
DOI:10.1111/iwj.12171