Acute onset supraclavicular lymphadenopathy coinciding with intramuscular mRNA vaccination against COVID-19 may be related to vaccine injection technique, Spain, January and February 2021

Monitoring adverse reactions following immunisation is essential, particularly for new vaccines such as those against COVID-19. We describe 20 cases of acute onset of a single supraclavicular lymphadenopathy manifesting between 24 h and 9 days after ipsilateral intramuscular administration of an mRN...

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Bibliographic Details
Published in:Euro surveillance : bulletin européen sur les maladies transmissibles 2021-03, Vol.26 (10), p.1
Main Authors: Fernández-Prada, María, Rivero-Calle, Irene, Calvache-González, Ana, Martinón-Torres, Federico
Format: Article
Language:English
Subjects:
COVID-19
COVID-19 - prevention & control
COVID-19 Vaccines - adverse effects
Humans
Immunization
Injections, Intramuscular - adverse effects
Lymphadenopathy - diagnosis
Lymphadenopathy - etiology
MicroRNAs
Pandemics
Rapid Communication
RNA, Messenger - administration & dosage
Spain
Vaccination - adverse effects
Vaccines
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Summary:Monitoring adverse reactions following immunisation is essential, particularly for new vaccines such as those against COVID-19. We describe 20 cases of acute onset of a single supraclavicular lymphadenopathy manifesting between 24 h and 9 days after ipsilateral intramuscular administration of an mRNA-based COVID-19 vaccine, referred to our WHO Collaborating Centre for Vaccine Safety. Our results indicate that the swelling of supraclavicular lymph nodes following immunisation may constitute a benign and self-limited condition, related to a higher than recommended injection site.
ISSN:1560-7917
1025-496X
1560-7917
DOI:10.2807/1560-7917.ES.2021.26.10.2100193