Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project

Aims. Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents based on ECG data from the CARDIOPED project, a large-scale ge...

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Bibliographic Details
Published in:Disease markers 2021, Vol.2021, p.6657982-5
Main Authors: Cismaru, Gabriel, Lazea, Cecilia, Mureşan, Lucian, Gusetu, Gabriel, Rosu, Radu, Pop, Dana, Zdrenghea, Dumitru, Farcaş, Anca Daniela, Căinap, Simona Sorana
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Age
Child
Children
EKG
Electrocardiography
Electrocardiography - methods
Electrocardiography - standards
Female
Heart rate
Humans
Male
P waves
Parents & parenting
Pediatrics
Population
Reference Values
Schools
Screening
Statistical analysis
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Summary:Aims. Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents based on ECG data from the CARDIOPED project, a large-scale general population of children who participated in a screening program in Transylvania, Romania. Methods and Results. A total of 22,411 ECGs of participants aged 6 to 18 years old from a school-based ECG screening were obtained between February 2015 and December 2015 in Transylvania, Romania. Three pediatric cardiologists manually reviewed each ECG. P-wave duration, voltage, axis, and correlation with gender and age were analyzed. The mean P-wave duration was 88±10.7 ms, with a maximum duration of 128 ms. P-wave showed a positive correlation with age but did not differ between sexes. There was a positive correlation between the P-wave duration and the heart rate, but not with the body max index. The mean P-wave axis was 40.4±31.1, and the mean P-wave amplitude was 0.12±0.03 mV. Conclusion. In this study on many pediatric subjects, we have provided normal limits for the P-wave in Romanian children aged 6-18 years. Our findings are useful for creating interpretation guidelines for pediatric ECG.
ISSN:0278-0240
1875-8630
DOI:10.1155/2021/6657982