Bronchopulmonary dysplasia precursors influence risk of white matter injury and adverse neurodevelopmental outcome in preterm infants

Background Cumulative supplemental oxygen (CSO) and cumulative mean airway pressure (CMAP) are associated with bronchopulmonary dysplasia (BPD) in preterm infants, but their relationships to white matter injury (WMI) and neurodevelopment have not been evaluated. Methods Preterm infants

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Bibliographic Details
Published in:Pediatric research 2021-08, Vol.90 (2), p.359-365
Main Authors: Grelli, Kimberly N., Keller, Roberta L., Rogers, Elizabeth E., Partridge, J. Colin, Xu, Duan, Barkovich, A. James, Gano, Dawn
Format: Article
Language:English
Subjects:
Age Factors
Bronchopulmonary Dysplasia - diagnosis
Bronchopulmonary Dysplasia - etiology
Bronchopulmonary Dysplasia - physiopathology
Child Development
Child Language
Child, Preschool
Clinical Research Article
Cognition
Cross-Sectional Studies
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Leukoencephalopathies - diagnostic imaging
Leukoencephalopathies - etiology
Leukoencephalopathies - physiopathology
Lung - physiopathology
Lung diseases
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Motor Activity
Nervous System - diagnostic imaging
Nervous System - growth & development
Newborn babies
Oxygen Inhalation Therapy - adverse effects
Pediatric Surgery
Pediatrics
Predictive Value of Tests
Premature babies
Pressure
Respiration
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
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Description
Summary:Background Cumulative supplemental oxygen (CSO) and cumulative mean airway pressure (CMAP) are associated with bronchopulmonary dysplasia (BPD) in preterm infants, but their relationships to white matter injury (WMI) and neurodevelopment have not been evaluated. Methods Preterm infants
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-020-01162-2