The Thickened Ligamentum Flavum: Is It Buckling or Enlargement?

• Published in: American journal of neuroradiology : AJNR 2010-11, Vol.31 (10), p.1813-1816
• Main Authors: CHOKSHI, F. H, QUENCER, R. M, SMOKER, W. R. K
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Humans; Inflammation - complications; Inflammation - pathology; Intervertebral Disc - pathology; Intervertebral Disc Degeneration - etiology; Intervertebral Disc Degeneration - immunology; Intervertebral Disc Degeneration - pathology; Intervertebral Disc Displacement - etiology; Intervertebral Disc Displacement - immunology; Intervertebral Disc Displacement - pathology; Investigative techniques, diagnostic techniques (general aspects); Ligamentum Flavum - immunology; Ligamentum Flavum - pathology; Lumbar Vertebrae - pathology; Magnetic Resonance Imaging - methods; Medical sciences; Nervous system; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Spine
• ISSN: 0195-6108; 1936-959X
• DOI: 10.3174/ajnr.A2241

Thickening of the LF is ascribed to buckling due to DSN. Uncertainty exists as to whether this can occur without DSN. Our primary hypothesis was that facet degenerative changes alone, independent of DSN, can thicken the LF. Our secondary hypothesis was that inflammatory changes surrounding degenerative facet joints may incite thickening. Fifty-two patients were divided into 1 of 3 groups: group 1 (normal lumbar spine, n = 21), group 2 (LF thickening and FH with normal height of the L4-5 disk, n = 18), and group 3 (LF thickening and FH with decreased height of the L4-5 disk, n = 13). LF thickness measured on axial T1WI at the midpoint of the LF length was compared with that in group 1. Facet joints were evaluated for spurring, joint fluid, and cortical irregularity, indicating facet degeneration. Enhancement of the facet joints and LF thickening were also evaluated (n = 2). The Student t test was used to compare groups. Normal LF thickness (group 1) was 3.1 mm, whereas LF thickness averaged 4.9 mm in group 2 and 5.3 mm in group 3 (both P < .001). Patients with asymmetric LF thickness showed greater LF thickness on the side with greater FH. There was more LF enhancement on the side with greater facet degenerative disease. LF thickening can be secondary to facet degenerative changes, independent of DSN. Inflammatory changes may be an inciting factor for LF thickening.