Quantification of internal carotid artery flow with digital subtraction angiography: validation of an optical flow approach with Doppler ultrasound

Digital subtraction angiography is the reference standard technique to evaluate intracranial vascular anatomy and used on the endovascular treatment of vascular diseases. A dedicated optical flow-based algorithm was applied to DSA to measure arterial flow. The first quantification results of interna...

Full description

Saved in:
Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2014-01, Vol.35 (1), p.156-163
Main Authors: Pereira, V Mendes, Ouared, R, Brina, O, Bonnefous, O, Satwiaski, J, Aerts, H, Ruijters, D, van Nijnatten, F, Perren, F, Bijlenga, P, Schaller, K, Lovblad, K-O
Format: Article
Language:English
Subjects:
Angiography, Digital Subtraction - methods
Blood Flow Velocity
Carotid Artery, Internal
Carotid Stenosis - diagnosis
Carotid Stenosis - physiopathology
Cerebral Angiography - methods
Cerebrovascular Circulation
Female
Humans
Interventional
Male
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Ultrasonography, Doppler - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Digital subtraction angiography is the reference standard technique to evaluate intracranial vascular anatomy and used on the endovascular treatment of vascular diseases. A dedicated optical flow-based algorithm was applied to DSA to measure arterial flow. The first quantification results of internal carotid artery flow validated with Doppler sonography are reported. We included 22 consecutive patients who underwent endovascular procedures. To assess the sensitivity of the algorithm to contrast agent-blood mixing dynamics, we acquired high-frame DSA series (60 images/s) with different injection rates: 1.5 mL/s (n = 19), 2.0 mL/s (n = 18), and 3.0 mL/s (n = 13). 3D rotational angiography was used to extract the centerline of the vessel and the arterial section necessary for volume flow calculation. Optical flow was used to measure flow velocities in straight parts of the ICAs; these data were further compared with Doppler sonography data. DSA mean flow rates were linearly regressed on Doppler sonography measurements, and regression slope coefficient bias from value 1 was analyzed within the 95% confidence interval. DSA mean flow rates measured with the optical flow approach significantly matched Doppler sonography measurements (slope regression coefficient, b = 0.83 ± 0.19, P = .05) for injection rate = 2.0 mL/s and circulating volumetric blood flow
ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A3662