MR Imaging of BK Virus Encephalitis

BK virus infection is most often associated with urologic disease in patients who have undergone renal or bone marrow transplantation. We report a rare case of biopsy-confirmed BK virus encephalitis in an immunocompromised patient with hemorrhagic cystitis, in whom dramatic imaging findings were pre...

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Bibliographic Details
Published in:American Journal of Neuroradiology 2006-05, Vol.27 (5), p.1016-1018
Main Authors: Friedman, D.P, Flanders, A.E
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
BK Virus
Brain
Encephalitis, Viral - diagnosis
Female
Fundamental and applied biological sciences. Psychology
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Imaging
Medical sciences
Nervous system
Perception
Polyomavirus Infections - diagnosis
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Tumor Virus Infections - diagnosis
Vision
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Summary:BK virus infection is most often associated with urologic disease in patients who have undergone renal or bone marrow transplantation. We report a rare case of biopsy-confirmed BK virus encephalitis in an immunocompromised patient with hemorrhagic cystitis, in whom dramatic imaging findings were present despite relatively mild clinical symptoms. MR imaging demonstrated widespread increased signal intensity on T2- and fluid-attenuated inversion recovery-weighted images, with restricted diffusion, in the cerebellum, cerebral white matter, and deep gray matter structures. The simultaneous presence of urologic abnormalities and neurologic deficits in certain immunocompromised patients should prompt consideration of BK virus encephalitis.
ISSN:0195-6108
1936-959X
1432-1920