Analysis of Slipstream Flow in a Wide-necked Basilar Artery Aneurysm: Evaluation of Potential Treatment Regimens

A replica of a lethal wide-necked basilar artery aneurysm was created by casting a deceased patient's brain vessels and then placing the replica in a circuit of pulsating optically clear non-Newtonian fluid. Individual fluid slipstreams were opacified with isobaric dyes, and images were recorde...

Full description

Saved in:
Bibliographic Details
Published in:American journal of neuroradiology 2001-04, Vol.22 (4), p.721-724
Main Authors: Imbesi, Steven G, Kerber, Charles W
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood Flow Velocity - physiology
Embolization, Therapeutic
Fatal Outcome
Female
Humans
Interventional
Intracranial Aneurysm - physiopathology
Intracranial Aneurysm - therapy
Medical sciences
Middle Aged
Models, Cardiovascular
Neurology
Rheology
Subarachnoid Hemorrhage - physiopathology
Subarachnoid Hemorrhage - therapy
Vascular diseases and vascular malformations of the nervous system
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A replica of a lethal wide-necked basilar artery aneurysm was created by casting a deceased patient's brain vessels and then placing the replica in a circuit of pulsating optically clear non-Newtonian fluid. Individual fluid slipstreams were opacified with isobaric dyes, and images were recorded on film. Studies were completed on the vascular replica, then were repeated, first after placement of a stent across the aneurysm neck and then after placement of Guglielmi detachable coils into the aneurysm sac through the stent. The slipstreams entered the untreated aneurysm via the distal aneurysm neck (the inflow zone), impacting against the distal lateral aneurysm wall. When the stent was placed across the aneurysm neck, the slipstreams lost coherence and did not strike the aneurysm sidewall. Placing the coils further disturbed and reduced aneurysmal flow, especially when the coils filled the inflow zone at the distal lateral aneurysm sac.
ISSN:0195-6108
1936-959X