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Early Characteristics of Sturge-Weber Syndrome Shown by Perfusion MR Imaging and Proton MR Spectroscopic Imaging

We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline witho...

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Published in:	American journal of neuroradiology : AJNR 2003-10, Vol.24 (9), p.1912-1915
Main Authors:	Lin, Doris D.M, Barker, Peter B, Kraut, Michael A, Comi, Anne
Format:	Article
Language:	English
Subjects:	Aspartic Acid - analogs & derivatives Aspartic Acid - analysis Biological and medical sciences Brain - pathology Brain Chemistry Cerebrovascular Circulation Choline - analysis Epilepsies, Partial - complications Humans Infant Magnetic Resonance Angiography Magnetic Resonance Spectroscopy Male Medical sciences Neurology Pediatrics Sturge-Weber Syndrome - diagnosis Sturge-Weber Syndrome - metabolism Sturge-Weber Syndrome - pathology Vascular diseases and vascular malformations of the nervous system
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container_title	American journal of neuroradiology : AJNR
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creator	Lin, Doris D.M Barker, Peter B Kraut, Michael A Comi, Anne
description	We report the case of a 9-month-old boy with Sturge-Weber syndrome and new onset of seizure. Perfusion MR imaging showed early changes compatible with impaired venous drainage in the affected hemisphere, whereas proton MR spectroscopic imaging revealed a focal parietal area of elevated choline without significant alteration of N-acetylaspartate levels. The perfusion and subtle metabolic abnormalities are comparable with the extent of the overlying leptomeningeal enhancement, illustrating the early pathophysiological manifestation of this disease.
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subjects	Aspartic Acid - analogs & derivatives Aspartic Acid - analysis Biological and medical sciences Brain - pathology Brain Chemistry Cerebrovascular Circulation Choline - analysis Epilepsies, Partial - complications Humans Infant Magnetic Resonance Angiography Magnetic Resonance Spectroscopy Male Medical sciences Neurology Pediatrics Sturge-Weber Syndrome - diagnosis Sturge-Weber Syndrome - metabolism Sturge-Weber Syndrome - pathology Vascular diseases and vascular malformations of the nervous system
title	Early Characteristics of Sturge-Weber Syndrome Shown by Perfusion MR Imaging and Proton MR Spectroscopic Imaging
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