Spinal Cord Involvement in Primary Angiitis of the Central Nervous System: A Report of Two Cases

We report two patients with suspected primary angiitis of the CNS who underwent serial contrast-enhanced MR imaging of the spinal cord. MR abnormalities were multiple and enhancing, and located within the cervical and thoracic cord. Brain MR findings and brain biopsy specimens were positive for prim...

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Bibliographic Details
Published in:American journal of neuroradiology : AJNR 2001-03, Vol.22 (3), p.577-582
Main Authors: Campi, Adriana, Benndorf, G, Martinelli, V, Terreni, M. R, Scotti, G
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Biopsy
Brain - pathology
Central Nervous System - blood supply
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Neurology
Spinal Cord - pathology
Spine
Vascular diseases and vascular malformations of the nervous system
Vasculitis - diagnosis
Vasculitis - pathology
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Summary:We report two patients with suspected primary angiitis of the CNS who underwent serial contrast-enhanced MR imaging of the spinal cord. MR abnormalities were multiple and enhancing, and located within the cervical and thoracic cord. Brain MR findings and brain biopsy specimens were positive for primary angiitis of the CNS. On follow-up MR studies, obtained after steroid and immunosuppressive therapy, a significant decrease in the number and size of the enhancing and nonenhancing abnormalities was observed, along with clinical improvement. Numerous small and enhancing abnormalities with a primarily posterior location, seen at the onset of the disease and resolved on follow-up studies, may be considered suggestive of a diagnosis of primary angiitis of the CNS.
ISSN:0195-6108
1936-959X