HIV-Risk Behavior Among Adults with Opioid Use Disorder During 12 Months Following Pre-trial Detention: Results from a Randomized Trial of Methadone Treatment

This was a three group randomized clinical trial of interim methadone and patient navigation involving 225 pre-trial detainees with opioid use disorder in Baltimore. The HIV Risk Assessment Battery (RAB) was administered at baseline (in jail), and at 6 and 12 months post-release. Generalized linear...

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Bibliographic Details
Published in:AIDS and behavior 2021-04, Vol.25 (4), p.1247-1256
Main Authors: Mitchell, M. M., Kelly, S. M., O’Grady, K. E., Jaffe, J. H., Mitchell, S. G., Schwartz, R. P.
Format: Article
Language:English
Subjects:
Adult
Baltimore - epidemiology
Clinical trials
Cocaine
Drug addiction
Drugs
Health Psychology
Health risks
HIV
HIV Infections - drug therapy
HIV Infections - epidemiology
HIV Infections - prevention & control
Human immunodeficiency virus
Humans
Infectious Diseases
Medicine
Medicine & Public Health
Methadone
Methadone - therapeutic use
Narcotics
Opioid-Related Disorders - epidemiology
Opioids
Original Paper
Pretrial detention
Public Health
Risk assessment
Risk behavior
Risk taking
Sex
Sexual behavior
Sexually transmitted diseases
Statistical models
STD
Substance abuse treatment
Substance use disorder
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Summary:This was a three group randomized clinical trial of interim methadone and patient navigation involving 225 pre-trial detainees with opioid use disorder in Baltimore. The HIV Risk Assessment Battery (RAB) was administered at baseline (in jail), and at 6 and 12 months post-release. Generalized linear mixed model analyses indicated the condition × time interaction effect failed to reach significance ( p s > .05) for both the drug risk and sex risk subscale scores. Therefore, findings suggest that there were no intervention effects on drug or sex risk behaviors. However, increased use of cocaine at baseline was associated with increases in drug- ( b  = .04, SE  = .02) and sex-risk ( b  = .01, SE  = .003) behaviors. These results suggest that interventions targeting cocaine use among pre-trial detainees may serve as a means of reducing HIV risk associated with drug- and sex-risk behaviors. Clinical Trials Registration: Clinicaltrials.gov NCT 02334215.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-020-03090-y