Marijuana-related Reversible Cerebral Vasoconstriction Syndrome

The legalization of recreational marijuana in some countries has been accompanied by an increased number of case reports of serious cardiovascular and cerebrovascular complications. However, there have been few studies describing the detailed clinical course of reversible cerebral vasospasm syndrome...

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Bibliographic Details
Published in:Internal Medicine 2021/03/01, Vol.60(5), pp.795-798
Main Authors: Mikami, Takahisa, Obata, Reiichiro, Steinberg, Daniel I., Skliut, Maryna, Boniece, Irene
Format: Article
Language:English
Subjects:
cannabinoid
Cannabis
Cannabis - adverse effects
Case Report
Case reports
Cerebrovascular Disorders
Humans
Infarction
Internal medicine
Marijuana
RCVS
Syndrome
Vasoconstriction
Vasospasm, Intracranial - diagnostic imaging
Vasospasm, Intracranial - etiology
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Summary:The legalization of recreational marijuana in some countries has been accompanied by an increased number of case reports of serious cardiovascular and cerebrovascular complications. However, there have been few studies describing the detailed clinical course of reversible cerebral vasospasm syndrome (RCVS) associated with marijuana use. We herein report a unique case of recurrent bi-fronto-parietal subcortical (watershed) infarction in the setting of chronic daily marijuana use for several years, with evidence of bilateral anterior cerebral artery vasoconstriction. The quick resolution of symptoms with treatment and the normalization of cerebral vasoconstriction on follow-up imaging lend high certainty to the diagnosis of RCVS.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.5687-20