Prevalence and risk factors of myasthenia gravis recurrence post-thymectomy

To evaluate the prevalence and the factors associated with recurrence of myasthenia gravis following thymectomy. Six electronic databases which reported on recurrence of myasthenia gravis following thymectomy and/or its risk factors from 1985 to 2018 were searched. Summary prevalence and risk values...

Full description

Saved in:
Bibliographic Details
Published in:Neurosciences (Riyadh, Saudi Arabia) Saudi Arabia), 2021-01, Vol.26 (1), p.4-14
Main Authors: Alqarni, Fatmah, Almalki, Daifallah, Aljohani, Ziyad, Ali, Abdulrahman, AlSaleem, Alanood, Alotaibi, Noura, Odeh, Shahla, Dalbhi, Sultan Al
Format: Article
Language:English
Subjects:
Databases, Factual
Humans
Myasthenia Gravis - epidemiology
Myasthenia Gravis - surgery
Prevalence
Recurrence
Risk Factors
Systematic Review
Thymectomy
Time Factors
Treatment Outcome
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the prevalence and the factors associated with recurrence of myasthenia gravis following thymectomy. Six electronic databases which reported on recurrence of myasthenia gravis following thymectomy and/or its risk factors from 1985 to 2018 were searched. Summary prevalence and risk values obtained based on the random effect models were reported. Seventy (70) papers containing 7,287 individuals with myasthenia gravis who received thymectomy as part of their management were retrieved. The patients had a mean follow-up of 4.65 years post-thymectomy. The prevalence of myasthenia gravis recurrence post-thymectomy was 18.0% (95% CI 14.7-22.0%; 1865/7287). Evident heterogeneity was observed (I =93.6%;
ISSN:1319-6138
1319-6138
DOI:10.17712/nsj.2021.1.20190041