Regional shape, global function and mechanics in right ventricular volume and pressure overload conditions: a three-dimensional echocardiography study

• Published in: The International Journal of Cardiovascular Imaging 2021-04, Vol.37 (4), p.1289-1299
• Main Authors: Bidviene, Jurate, Muraru, Denisa, Maffessanti, Francesco, Ereminiene, Egle, Kovács, Attila, Lakatos, Bálint, Vaskelyte, Jolanta-Justina, Zaliunas, Remigijus, Surkova, Elena, Parati, Gianfranco, Badano, Luigi P.
• Format: Article
• Language: English
• Subjects: Apexes; Cardiac Imaging; Cardiology; Cardiovascular disease; Concavity; Congenital diseases; Contraction; Convexity; Curvature; Diastole; Echocardiography; Flat surfaces; Heart; Imaging; Mechanics (physics); Medicine; Medicine & Public Health; Original Paper; Overloading; Pressure; Radiology; Regional analysis; Septum; Systole; Three dimensional analysis; Ventricle
• ISSN: 1569-5794; 1573-0743; 1875-8312
• DOI: 10.1007/s10554-020-02117-8

Our aim was to assess the regional right ventricular (RV) shape changes in pressure and volume overload conditions and their relations with RV function and mechanics. The end-diastolic and end-systolic RV endocardial surfaces were analyzed with three-dimensional echocardiography (3DE) in 33 patients with RV volume overload (rToF), 31 patients with RV pressure overload (PH), and 60 controls. The mean curvature of the RV inflow (RVIT) and outflow (RVOT) tracts, RV apex and body (both divided into free wall (FW) and septum) were measured. Zero curvature defined a flat surface, whereas positive or negative curvature indicated convexity or concavity, respectively. The longitudinal and radial RV wall motions were also obtained. rToF and PH patients had flatter FW (body and apex) and RVIT, more convex interventricular septum (body and apex) and RVOT than controls. rToF demonstrated a less bulging interventricular septum at end-systole than PH patients, resulting in a more convex shape of the RVFW (r = − 0.701, p