Longitudinal control of blood pressure among a cohort of Ghanaians with hypertension: A multicenter, hospital‐based study

• Published in: The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2020-06, Vol.22 (6), p.949-958
• Main Authors: Sarfo, Fred S., Mobula, Linda, Plange‐Rhule, Jacob, Gebregziabher, Mulugeta, Ansong, Daniel, Sarfo‐Kantanka, Osei, Arthur, Lynda, Sablah, Jasper, Gavor, Edith, Burnham, Gilbert, Ofori‐Adjei, David
• Format: Article
• Language: English
• Subjects: adherence; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; Blood Pressure - drug effects; BP control; Cohort Studies; Epidemiology; Female; Ghana; Ghana - epidemiology; Hospitals; Humans; Hypertension - diagnosis; Hypertension - epidemiology; Hypertension - therapy; Longitudinal Studies; Male; Middle Aged; Original Paper; prospective; Prospective Studies; Risk Factors; sub‐Saharan Africa; therapeutic inertia
• ISSN: 1524-6175; 1751-7176
• DOI: 10.1111/jch.13873

There are limited data on factors associated with longitudinal control of blood pressure (BP) among Ghanaians on antihypertensive treatment. We sought to evaluate associations between prospective BP control and 24 putative factors within socio‐demographic, biological, and organizational domains. This is a cohort study involving 1867 (65%) adults with hypertension and 1006 (35%) with both hypertension and diabetes mellitus at five public hospitals. Clinic BP was measured every 2 months for 18 months of follow‐up. A multivariate logistic regression analysis was fitted via generalized linear mixed models to identify factors associated with clinic BP ≥ 140/90 mm Hg at each clinic visit during follow‐up. Mean age of study participants was 58.9 ± 16.6 years and 76.8% were females. Proportions with controlled BP increased from 46.3% at baseline to 59.8% at month 18, P