Arterial stiffness and subendocardial viability ratio in patients with peripheral arterial disease

Arterial stiffening is a hallmark of the aging process and atherosclerosis, including peripheral arterial disease (PAD). We investigated the associations between carotid‐femoral pulse wave velocity (c‐fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and sube...

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Bibliographic Details
Published in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2018-03, Vol.20 (3), p.478-484
Main Authors: Scandale, Giovanni, Dimitrov, Gabriel, Recchia, Martino, Carzaniga, Gianni, Minola, Marzio, Perilli, Edoardo, Carotta, Maria, Catalano, Mariella
Format: Article
Language:English
Subjects:
Aged
Ankle Brachial Index
Arterial Stiffness
Female
Humans
Hypertension - complications
Male
Middle Aged
Original Paper
peripheral arterial disease
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - physiopathology
Pulse Wave Analysis
subendocardial viability
Vascular Stiffness
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Summary:Arterial stiffening is a hallmark of the aging process and atherosclerosis, including peripheral arterial disease (PAD). We investigated the associations between carotid‐femoral pulse wave velocity (c‐fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and subendocardial viability ratio (SEVR), an indicator of cardiac perfusion. The c‐fPWV, Aix@HR75, and SEVR was estimated using applanation tonometry. The ankle systolic pressure measurements for the calculation of the ABI were obtained using an 8‐mHz Doppler probe. The study group included 555 subjects, mean age 63 ± 11 years (248 PAD (ABI 
ISSN:1524-6175
1751-7176
DOI:10.1111/jch.13213