Arterial stiffness and subendocardial viability ratio in patients with peripheral arterial disease

Arterial stiffening is a hallmark of the aging process and atherosclerosis, including peripheral arterial disease (PAD). We investigated the associations between carotid‐femoral pulse wave velocity (c‐fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and sube...

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Published in:The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2018-03, Vol.20 (3), p.478-484
Main Authors: Scandale, Giovanni, Dimitrov, Gabriel, Recchia, Martino, Carzaniga, Gianni, Minola, Marzio, Perilli, Edoardo, Carotta, Maria, Catalano, Mariella
Format: Article
Language:English
Subjects:
Aged
Ankle Brachial Index
Arterial Stiffness
Female
Humans
Hypertension - complications
Male
Middle Aged
Original Paper
peripheral arterial disease
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - physiopathology
Pulse Wave Analysis
subendocardial viability
Vascular Stiffness
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cited_by cdi_FETCH-LOGICAL-c4153-2f50c0126ec5f6330d779b300a276fdb0ecbe07323b75a3a5d7324d4173799d53
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container_title The journal of clinical hypertension (Greenwich, Conn.)
container_volume 20
creator Scandale, Giovanni
Dimitrov, Gabriel
Recchia, Martino
Carzaniga, Gianni
Minola, Marzio
Perilli, Edoardo
Carotta, Maria
Catalano, Mariella
description Arterial stiffening is a hallmark of the aging process and atherosclerosis, including peripheral arterial disease (PAD). We investigated the associations between carotid‐femoral pulse wave velocity (c‐fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and subendocardial viability ratio (SEVR), an indicator of cardiac perfusion. The c‐fPWV, Aix@HR75, and SEVR was estimated using applanation tonometry. The ankle systolic pressure measurements for the calculation of the ABI were obtained using an 8‐mHz Doppler probe. The study group included 555 subjects, mean age 63 ± 11 years (248 PAD (ABI 
doi_str_mv 10.1111/jch.13213
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We investigated the associations between carotid‐femoral pulse wave velocity (c‐fPWV), augmentation index corrected for heart rate (Aix@HR75), ankle brachial index (ABI), and subendocardial viability ratio (SEVR), an indicator of cardiac perfusion. The c‐fPWV, Aix@HR75, and SEVR was estimated using applanation tonometry. The ankle systolic pressure measurements for the calculation of the ABI were obtained using an 8‐mHz Doppler probe. The study group included 555 subjects, mean age 63 ± 11 years (248 PAD (ABI &lt; 1.0), and 307 non‐PAD (ABI ≥ 1.0 ≤ 1.3). After the stepwise selection process in both PAD and non‐PAD patients SEVR was not related to c‐fPWV and ABI (P = .154; P = .156) and (P = .101; P = .402), respectively. In PAD patients, SEVR was negatively related to Aix@HR75 (P &lt; .0001) and aortic PP (P = .0005). 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subjects Aged
Ankle Brachial Index
Arterial Stiffness
Female
Humans
Hypertension - complications
Male
Middle Aged
Original Paper
peripheral arterial disease
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - physiopathology
Pulse Wave Analysis
subendocardial viability
Vascular Stiffness
title Arterial stiffness and subendocardial viability ratio in patients with peripheral arterial disease
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