COVID-19 Vaccine and Hyperosmolar Hyperglycemic State

Coronavirus disease 2019 (COVID-19) is a multi-system disease that causes multiple complications. It is linked to the development of new-onset diabetes or unmasking of underlying diabetes. Despite the uncertain exact mechanism, pancreatic angiotensin-converting enzyme 2 (ACE2) receptor, the main enz...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2021-03, Vol.13 (3), p.e14125
Main Authors: Abu-Rumaileh, Mohammed A, Gharaibeh, Ahmad M, Gharaibeh, Naser Eddin
Format: Article
Language:English
Subjects:
Endocrinology/Diabetes/Metabolism
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Summary:Coronavirus disease 2019 (COVID-19) is a multi-system disease that causes multiple complications. It is linked to the development of new-onset diabetes or unmasking of underlying diabetes. Despite the uncertain exact mechanism, pancreatic angiotensin-converting enzyme 2 (ACE2) receptor, the main enzyme related to COVID-19 pathophysiology has been implied. COVID-19 vaccine was authorized to help control the rapid spread of COVID-19 disease. We report a case of new-onset diabetes type 2 presenting as hyperosmolar hyperglycemic state (HHS) in a patient after receiving COVID-19 vaccine with some literature review of the potential mechanisms by which COVID-19 may cause new-onset diabetes type 2.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.14125