Factor XIII Deficiency Associated With Noonan Syndrome

Noonan syndrome (NS) is an autosomal dominant disorder with multisystem involvement. NS can be associated with bleeding disorders due to defects in platelet function or coagulation factors and diagnosis can be challenging. Factor XIII (FXIII) deficiency is uncommon in patients with NS. We present a...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2021-03, Vol.13 (3), p.e14150
Main Authors: Kharel, Zeni, Katel, Anjan, Neupane, Arun, Panday, Pradumna, Aryal, Madan
Format: Article
Language:English
Subjects:
Genetics
Hematology
Internal Medicine
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Description
Summary:Noonan syndrome (NS) is an autosomal dominant disorder with multisystem involvement. NS can be associated with bleeding disorders due to defects in platelet function or coagulation factors and diagnosis can be challenging. Factor XIII (FXIII) deficiency is uncommon in patients with NS. We present a case of NS who presented with bleeding in both thighs and was diagnosed to have deficiency in FXIII.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.14150