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THE ROLE OF BONE MARROW miRNA IN ERYTHROPOIETIC DYSFUNCTION FOLOWING SEVERE TRAUMA

Assessment of the bone marrow miRNA profile in trauma patients compared to those undergoing elective hip replacement revealed the differential expression of miR-150, miR-223, miR-15a, and miR-24. These miRNAs all play a role in decreased erythroid progenitor cell growth and provide important insight...

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Published in:Surgery 2021-01, Vol.169 (5), p.1206-1212
Main Authors: Apple, Camille G., Miller, Elizabeth S., Kannan, Kolenkode B., Stortz, Julie A., Loftus, Tyler J., Lopez, Maria Cecilia, Parvataneni, Hari K., Patrick, Matthew, Hagen, Jennifer E., Baker, Henry V., Efron, Philip A., Mohr, Alicia M.
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container_end_page 1212
container_issue 5
container_start_page 1206
container_title Surgery
container_volume 169
creator Apple, Camille G.
Miller, Elizabeth S.
Kannan, Kolenkode B.
Stortz, Julie A.
Loftus, Tyler J.
Lopez, Maria Cecilia
Parvataneni, Hari K.
Patrick, Matthew
Hagen, Jennifer E.
Baker, Henry V.
Efron, Philip A.
Mohr, Alicia M.
description Assessment of the bone marrow miRNA profile in trauma patients compared to those undergoing elective hip replacement revealed the differential expression of miR-150, miR-223, miR-15a, and miR-24. These miRNAs all play a role in decreased erythroid progenitor cell growth and provide important insight to the erythropoietic dysfunction seen after trauma.
doi_str_mv 10.1016/j.surg.2020.11.029
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title THE ROLE OF BONE MARROW miRNA IN ERYTHROPOIETIC DYSFUNCTION FOLOWING SEVERE TRAUMA
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