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TLR2 and TLR4 Gene Expression in Peripheral Monocytes in Nondiabetic Hypertensive Patients: The Effect of Intensive Blood Pressure–Lowering
J Clin Hypertens (Greenwich). 2012; 14:330–335. ©2012 Wiley Periodicals, Inc. The activation of innate immune receptors, such as Toll‐like receptors (TLRs), participates in the pathogenesis of cardiovascular diseases. The authors evaluated TLR2 and TLR4 gene expression in the peripheral monocytes of...
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Published in: | The journal of clinical hypertension (Greenwich, Conn.) Conn.), 2012-05, Vol.14 (5), p.330-335 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | J Clin Hypertens (Greenwich). 2012; 14:330–335. ©2012 Wiley Periodicals, Inc.
The activation of innate immune receptors, such as Toll‐like receptors (TLRs), participates in the pathogenesis of cardiovascular diseases. The authors evaluated TLR2 and TLR4 gene expression in the peripheral monocytes of nondiabetic hypertensive patients compared with normotensive individuals and investigated the effect of intensive systolic blood pressure (SBP)–lowering. Included were 43 nondiabetic hypertensive patients with essential hypertension who were randomly assigned to an intensive treatment arm, with an SBP target of |
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ISSN: | 1524-6175 1751-7176 |
DOI: | 10.1111/j.1751-7176.2012.00620.x |